Activins and inhibins: roles in development, physiology, and disease

M Namwanje, CW Brown - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Since their original discovery as regulators of follicle-stimulating hormone (FSH) secretion
and erythropoiesis, the TGF-β family members activin and inhibin have been shown to …

Cooperation of liver cells in health and disease: with 18 tables

Z Kmiec - 2001 - books.google.com
It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer
cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better …

Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines

N Venteclef, V Guglielmi, E Balse, B Gaborit… - European heart …, 2015 - academic.oup.com
Aims Recent studies have reported a relationship between the abundance of epicardial
adipose tissue (EAT) and the risk of cardiovascular diseases including atrial fibrillation (AF) …

Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.

JP Iredale, RC Benyon, J Pickering… - The Journal of …, 1998 - Am Soc Clin Investig
Liver fibrosis results from the excessive secretion of matrix proteins by hepatic stellate cells
(HSC), which proliferate during fibrotic liver injury. We have studied a model of spontaneous …

Epicardial adipose tissue and atrial fibrillation

SN Hatem, P Sanders - Cardiovascular research, 2014 - academic.oup.com
Atrial fibrillation (AF) is the most frequent cardiac arrhythmia in clinical practice. AF is often
associated with profound functional and structural alterations of the atrial myocardium that …

Transforming growth factor β and the liver

MD Bissell, D Roulot, J George - Hepatology, 2001 - journals.lww.com
Building of tissue, whether in the embryo or after injury in the adult, requires coordination of
several important cellular actions including fibrogenesis, proliferation, migration, contraction …

Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling

C Besson-Fournier, C Latour, L Kautz… - Blood, The Journal …, 2012 - ashpublications.org
Anemia is very common in patients suffering from infections or chronic inflammation and can
add substantially to the morbidity of the underlying disease. It is mediated by excessive …

The regulation and functions of activin and follistatin in inflammation and immunity

MP Hedger, WR Winnall, DJ Phillips… - Vitamins & Hormones, 2011 - Elsevier
The activins are members of the transforming growth factor β superfamily with broad and
complex effects on cell growth and differentiation. Activin A has long been known to be a …

Roles of activin in tissue repair, fibrosis, and inflammatory disease

S Werner, C Alzheimer - Cytokine & growth factor reviews, 2006 - Elsevier
Activins are transforming growth factor β superfamily members, which were originally
identified as inducers of follicle-stimulating hormone release from the pituitary. In recent …

Hepatic lymphatic vascular system in health and disease

J Jeong, M Tanaka, Y Iwakiri - Journal of hepatology, 2022 - Elsevier
In recent years, significant advances have been made in the study of lymphatic vessels with
the identification of their specific markers and the development of research tools that have …