Nano-omics: nanotechnology-based multidimensional harvesting of the blood-circulating cancerome
Over the past decade, the development of 'simple'blood tests that enable cancer screening,
diagnosis or monitoring and facilitate the design of personalized therapies without the need …
diagnosis or monitoring and facilitate the design of personalized therapies without the need …
Emerging nanotechnology for Alzheimer's disease: From detection to treatment
N Song, S Sun, K Chen, Y Wang, H Wang… - Journal of Controlled …, 2023 - Elsevier
Abstract Alzheimer's disease (AD), one of the most common chronic neurodegenerative
diseases, is characterized by memory impairment, synaptic dysfunction, and character …
diseases, is characterized by memory impairment, synaptic dysfunction, and character …
Nanoparticle protein corona evolution: from biological impact to biomarker discovery
Nanoparticles exposed to biological fluids such as blood, quickly interact with their
surrounding milieu resulting in a biological coating that results in large part as a function of …
surrounding milieu resulting in a biological coating that results in large part as a function of …
Omics-based biomarkers discovery for Alzheimer's disease
Q Aerqin, ZT Wang, KM Wu, XY He, Q Dong… - Cellular and Molecular …, 2022 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disorders presenting with
the pathological hallmarks of amyloid plaques and tau tangles. Over the past few years …
the pathological hallmarks of amyloid plaques and tau tangles. Over the past few years …
Combinatorial power of cfDNA, CTCs and EVs in oncology
Liquid biopsy is a promising technique for clinical management of oncological patients. The
diversity of analytes circulating in the blood useable for liquid biopsy testing is enormous …
diversity of analytes circulating in the blood useable for liquid biopsy testing is enormous …
The lipidomic profile of the nanoparticle-biomolecule corona reflects the diversity of plasma lipids
L Papafilippou, A Nicolaou, AC Kendall… - Nanoscale, 2023 - pubs.rsc.org
The spontaneous self-assembly of biomolecules around the surface of nanoparticles (NPs)
once exposed to plasma and other biofluids, has been termed the 'biomolecule corona' …
once exposed to plasma and other biofluids, has been termed the 'biomolecule corona' …
Isolation methods commonly used to study the liposomal protein corona suffer from contamination issues
The liposomal protein corona has been the focus of numerous studies, but there is still no
consensus regarding its extent and composition. Rather, the literature is full of conflicting …
consensus regarding its extent and composition. Rather, the literature is full of conflicting …
Unraveling the effect of breast cancer patients' plasma on the targeting ability of folic acid-modified chitosan nanoparticles
The formation of protein corona (PC) around nanoparticles (NPs) has been reported inside
biological conditions. This effect can alter delivery capacity toward the targeted tissues …
biological conditions. This effect can alter delivery capacity toward the targeted tissues …
Physiology, pathology and the biomolecular corona: the confounding factors in nanomedicine design
The biomolecular corona that forms on nanomedicines in different physiological and
pathological environments confers a new biological identity. How the recipient biological …
pathological environments confers a new biological identity. How the recipient biological …
Significance and implications of nanoparticle–biological corona fingerprints in diagnosis, prognosis, and therapeutics for diverse disorders
J Ren, S Zhang, S Liu - Nanoscale, 2023 - pubs.rsc.org
Upon entering a biological environment, the surface of nanoparticles (NPs) is rapidly coated
by various biomolecules (typically proteins), herein referred to as the biological corona …
by various biomolecules (typically proteins), herein referred to as the biological corona …