Molecular biomarkers for the early detection of ovarian cancer

R Zhang, MKY Siu, HYS Ngan, KKL Chan - International Journal of …, 2022 - mdpi.com
Ovarian cancer is the deadliest gynecological cancer, leading to over 152,000 deaths each
year. A late diagnosis is the primary factor causing a poor prognosis of ovarian cancer and …

[HTML][HTML] Updates and new options in advanced epithelial ovarian cancer treatment

KC Kurnit, GF Fleming, E Lengyel - Obstetrics & Gynecology, 2021 - journals.lww.com
Financial Disclosure Ernst Lengyel disclosed that money was paid to his institution from
AbbVie (funding preclinical studies), NCI (RO1 grants), and the Ovarian Cancer Research …

Integrating artificial intelligence and nanotechnology for precision cancer medicine

O Adir, M Poley, G Chen, S Froim, N Krinsky… - Advanced …, 2020 - Wiley Online Library
Artificial intelligence (AI) and nanotechnology are two fields that are instrumental in realizing
the goal of precision medicine—tailoring the best treatment for each cancer patient. Recent …

Precision diagnostics: moving towards protein biomarker signatures of clinical utility in cancer

CAK Borrebaeck - Nature Reviews Cancer, 2017 - nature.com
Interest in precision diagnostics has been fuelled by the concept that early detection of
cancer would benefit patients; that is, if detected early, more tumours should be resectable …

Predicting the risk of malignancy in adnexal masses based on the Simple Rules from the International Ovarian Tumor Analysis group

D Timmerman, B Van Calster, A Testa, L Savelli… - American journal of …, 2016 - Elsevier
Background Accurate methods to preoperatively characterize adnexal tumors are pivotal for
optimal patient management. A recent metaanalysis concluded that the International …

Current and emerging methods for ovarian cancer screening and diagnostics: a comprehensive review

JM Liberto, SY Chen, IM Shih, TH Wang, TL Wang… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

The role of CA 125 as tumor marker: biochemical and clinical aspects

P Bottoni, R Scatena - Advances in cancer biomarkers: from biochemistry …, 2015 - Springer
CA 125 also known as mucin 16 or MUC16 is a large membrane glycoprotein belonging to
the wide mucin family, encoded by the homonymous MUC16 gene. Following its discovery …

Presurgical diagnosis of adnexal tumours using mathematical models and scoring systems: a systematic review and meta-analysis

J Kaijser, A Sayasneh, K Van Hoorde… - Human reproduction …, 2014 - academic.oup.com
BACKGROUND Characterizing ovarian pathology is fundamental to optimizing
management in both pre-and post-menopausal women. Inappropriate referral to oncology …

Validation of American college of radiology ovarian-adnexal reporting and data system ultrasound (O-RADS US): analysis on 1054 adnexal masses

L Cao, M Wei, Y Liu, J Fu, H Zhang, J Huang, X Pei… - Gynecologic …, 2021 - Elsevier
Objective To assess the diagnostic performance and inter-observer agreement of the
American College of Radiology (ACR) Ovarian-Adnexal Reporting and Data System …

First international consensus report on adnexal masses: management recommendations

P Glanc, B Benacerraf, T Bourne… - … of Ultrasound in …, 2017 - Wiley Online Library
The First International Consensus Conference on Adnexal Masses was convened to
thoroughly examine the state of the science and to formulate recommendations for clinical …