Early-onset sepsis remains a common and serious problem for neonates, especially preterm
infants. Group B streptococcus (GBS) is the most common etiologic agent, while Escherichia …

Viral infections during pregnancy have long been considered benign conditions with a few
notable exceptions, such as herpes virus. The recent Ebola outbreak and other viral …

Rapid diagnosis and treatment of infectious meningitis and encephalitis are critical to
minimize morbidity and mortality. Comprehensive testing of cerebrospinal fluid (CSF) often …

Some maternal infections, contracted before or during pregnancy, can be transmitted to the
fetus, during gestation (congenital infection), during labor and childbirth (perinatal infection) …

Pediatric acute liver failure (PALF) is a rare, rapidly progressive clinical syndrome with
significant morbidity and mortality. The phenotype of PALF manifests as abrupt onset liver …

The human microbiome functions as an intricate and coordinated microbial network,
residing throughout the mucosal surfaces of the skin, oral cavity, gastrointestinal tract …

Eight of the more than 80 known herpesviruses are human pathogens. Human herpes
simplex virus (HSV) is a contagious infection with a large reservoir in the general population …

Context Neonatal herpes most commonly results from fetal exposure to infected maternal
genital secretions at the time of delivery. The risk of transmission from mother to infant as it …

Herpes simplex virus (HSV) infections of humans were first documented in ancient Greece.
Greek scholars, particularly Hippocrates, used the word" herpes," meaning to creep or crawl …

Whether it is caused by herpes simplex virus (HSV) type 1 or type 2, neonatal HSV infection
is a devastating disease if untreated, and more than 30% of pregnant women in the United …