AU-rich elements and associated factors: are there unifying principles?

C Barreau, L Paillard, HB Osborne - Nucleic acids research, 2005 - academic.oup.com
The control of mRNA stability is an important process that allows cells to not only limit, but
also rapidly adjust, the expression of regulatory factors whose over expression may be …

RNA binding proteins in intestinal epithelial biology and colorectal cancer

P Chatterji, AK Rustgi - Trends in molecular medicine, 2018 - cell.com
The intestinal epithelium is highly proliferative and consists of crypt invaginations that house
stem cells and villus projections with differentiated cells. There exists a dynamic equilibrium …

Hairpin RNA: a secondary structure of primary importance

P Svoboda, AD Cara - Cellular and Molecular Life Sciences CMLS, 2006 - Springer
An RNA hairpin is an essential secondary structure of RNA. It can guide RNA folding,
determine interactions in a ribozyme, protect messenger RNA (mRNA) from degradation …

The gene associated with trichorhinophalangeal syndrome in humans is overexpressed in breast cancer

L Radvanyi, D Singh-Sandhu… - Proceedings of the …, 2005 - National Acad Sciences
A comprehensive differential gene expression screen on a panel of 54 breast tumors and>
200 normal tissue samples using DNA microarrays revealed 15 genes specifically …

Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing …

K Buchet-Poyau, J Courchet, HL Hir… - Nucleic acids …, 2007 - academic.oup.com
Abstract In Caenorhabditis elegans, the Mex-3 protein is a translational regulator that
specifies the posterior blastomere identity in the early embryo and contributes to the …

Translational Regulators Maintain Totipotency in the Caenorhabditis elegans Germline

R Ciosk, M DePalma, JR Priess - Science, 2006 - science.org
The molecular mechanisms that maintain totipotency of the germline are not well
understood. Here, we show that two conserved translational regulators, MEX-3 and GLD-1 …

Turnover of AU‐rich‐containing mRNAs during stress: a matter of survival

C von Roretz, SD Marco, R Mazroui… - Wiley Interdisciplinary …, 2011 - Wiley Online Library
Cells undergo various adaptive measures in response to stress. Among these are specific
changes in the posttranscriptional regulation of various genes. In particular, the turnover of …

Regulation of ABCG2 expression at the 3′ untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in …

KKW To, Z Zhan, T Litman, SE Bates - Molecular and cellular …, 2008 - Am Soc Microbiol
ABCG2 is recognized as an important efflux transporter in clinical pharmacology and is
potentially important in resistance to chemotherapeutic drugs. To identify epigenetic …

DCA1 acts as a transcriptional co-activator of DST and contributes to drought and salt tolerance in rice

LG Cui, JX Shan, M Shi, JP Gao, HX Lin - PLoS genetics, 2015 - journals.plos.org
Natural disasters, including drought and salt stress, seriously threaten food security. In
previous work we cloned a key zinc finger transcription factor gene, D rought and S alt T …

CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness

B Pereira, S Sousa, R Barros, L Carreto… - Nucleic acids …, 2013 - academic.oup.com
The homeobox transcription factor CDX2 plays a crucial role in intestinal cell fate
specification, both during normal development and in tumorigenic processes involving …