Harnessing genomic information for livestock improvement

M Georges, C Charlier, B Hayes - Nature Reviews Genetics, 2019 - nature.com
The world demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has a minimal impact on the environment will …

Genomic selection and its research progress in aquaculture breeding

H Song, T Dong, X Yan, W Wang, Z Tian… - Reviews in …, 2023 - Wiley Online Library
Since its introduction in 2001, genomic selection (GS) has progressed rapidly. As a research
and application hot topic, GS has led to a revolution in the field of animal and plant breeding …

Comprehensive analyses of 723 transcriptomes enhance genetic and biological interpretations for complex traits in cattle

L Fang, W Cai, S Liu, O Canela-Xandri, Y Gao… - Genome …, 2020 - genome.cshlp.org
By uniformly analyzing 723 RNA-seq data from 91 tissues and cell types, we built a
comprehensive gene atlas and studied tissue specificity of genes in cattle. We demonstrated …

[HTML][HTML] Symposium review: How to implement genomic selection

PM VanRaden - Journal of Dairy Science, 2020 - Elsevier
Genomic selection was adopted very quickly in the 10 yr after first implementation, and
breeders continue to find new uses for genomic testing. Breeding values with higher …

Quantifying the contribution of sequence variants with regulatory and evolutionary significance to 34 bovine complex traits

R Xiang, I Berg, IM MacLeod… - Proceedings of the …, 2019 - National Acad Sciences
Many genome variants shaping mammalian phenotype are hypothesized to regulate gene
transcription and/or to be under selection. However, most of the evidence to support this …

Comprehensive transcriptome and methylome analysis delineates the biological basis of hair follicle development and wool-related traits in Merino sheep

B Zhao, H Luo, J He, X Huang, S Chen, X Fu, W Zeng… - BMC biology, 2021 - Springer
Background Characterization of the molecular mechanisms underlying hair follicle
development is of paramount importance in the genetic improvement of wool-related traits in …

Using imputation-based whole-genome sequencing data to improve the accuracy of genomic prediction for combined populations in pigs

H Song, S Ye, Y Jiang, Z Zhang, Q Zhang… - Genetics Selection …, 2019 - Springer
Background For genomic selection in populations with a small reference population,
combining populations of the same breed or populations of related breeds is an effective …

Use of gene expression and whole-genome sequence information to improve the accuracy of genomic prediction for carcass traits in Hanwoo cattle

S de Las Heras-Saldana, BI Lopez… - Genetics Selection …, 2020 - Springer
Background In this study, we assessed the accuracy of genomic prediction for carcass
weight (CWT), marbling score (MS), eye muscle area (EMA) and back fat thickness (BFT) in …

Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases

L Lin, Y Liu, F Xu, J Huang, TF Daugaard… - …, 2018 - academic.oup.com
Background Fusion of DNA methyltransferase domains to the nuclease-deficient clustered
regularly interspaced short palindromic repeat (CRISPR) associated protein 9 (dCas9) has …

Functional annotation of the cattle genome through systematic discovery and characterization of chromatin states and butyrate-induced variations

L Fang, S Liu, M Liu, X Kang, S Lin, B Li, EE Connor… - BMC biology, 2019 - Springer
Background The functional annotation of genomes, including chromatin accessibility and
modifications, is important for understanding and effectively utilizing the increased amount of …