Cilia, organelles that move to execute functions like fertilization and signal to execute
functions like photoreception and embryonic patterning, are composed of a core of nine-fold …

Abstract The Bardet Biedl syndrome (BBS) is a rare inherited disorder considered a model of
non-motile ciliopathy. It is in fact caused by mutations of genes encoding for proteins mainly …

Signaling receptors dynamically exit cilia upon activation of signaling pathways such as
Hedgehog. Here, we find that when activated G protein-coupled receptors (GPCRs) fail to …

Bardet‐Biedl syndrome (BBS) is a recessive genetic disease causing multiple organ
anomalies. Most patients carry mutations in genes encoding for the subunits of the BBSome …

The primary cilium is a highly specialized and evolutionary conserved organelle in
eukaryotes that plays a significant role in cell signaling and trafficking. Over the past few …

Degenerative disc disease (DDD) is associated with intervertebral disc degeneration of
spinal instability. Here, we report that the cilia of nucleus pulposus (NP) cells mediate …

Mechanical stimulation of primary cilia in osteocytes and osteoblasts has been proposed as
a mechanism that participates in bone cell survival and skeletal remodeling. Among different …

Chirality is a common phenomenon within odorants. Most pairs of enantiomers show only
moderate differences in odor quality. One example for enantiomers that are easily …

Primary cilia are sensory membrane protrusions whose dysfunction causes ciliopathies.
INPP5E is a ciliary phosphoinositide phosphatase mutated in ciliopathies like Joubert …

Cilium, a tiny microtubule‐based cellular appendage critical for cell signalling and
physiology, displays a large variety of receptors. The composition and turnover of ciliary …