COVID-19 vaccine development: milestones, lessons and prospects

M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …

Counting on COVID-19 vaccine: insights into the current strategies, progress and future challenges

R Kandimalla, P Chakraborty, J Vallamkondu… - Biomedicines, 2021 - mdpi.com
The emergence of a novel coronavirus viz., severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) in late 2019 and its subsequent substantial spread produced the …

Impact of SARS-CoV-2 Gamma lineage introduction and COVID-19 vaccination on the epidemiological landscape of a Brazilian city

CA Banho, L Sacchetto, GRF Campos, C Bittar… - Communications …, 2022 - nature.com
Background: The emergence of the Brazilian variant of concern, Gamma lineage (P. 1),
impacted the epidemiological profile of COVID-19 cases due to its higher transmissibility …

Immune profile and clinical outcome of breakthrough cases after vaccination with an inactivated SARS-CoV-2 vaccine

LF Duarte, NMS Gálvez, C Iturriaga… - Frontiers in …, 2021 - frontiersin.org
Constant efforts to prevent infections by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are actively carried out around the world. Several vaccines are currently …

Efficacy and safety of COVID-19 vaccines—an update

E Sharma, S Revinipati, S Bhandari, S Thakur, S Goyal… - Diseases, 2022 - mdpi.com
A few centuries ago, the first vaccine vial was formulated, and since then, they have resulted
in an eminent reduction in infectious diseases associated morbidity and mortality. The …

Emerging SARS-CoV-2 genotypes show different replication patterns in human pulmonary and intestinal epithelial cells

GAP de Souza, M Le Bideau, C Boschi, L Ferreira… - Viruses, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) quickly spread
worldwide following its emergence in Wuhan, China, and hit pandemic levels. Its …

SARS-CoV-2 genomic surveillance in Brazil: a systematic review with scientometric analysis

D Menezes, PLC Fonseca, JLF de Araújo, RP Souza - Viruses, 2022 - mdpi.com
Several studies have monitored the SARS-CoV-2 variants in Brazil throughout the
pandemic. Here, we systematically reviewed and conducted a scientometric analysis of the …

Novel coronavirus mutations: Vaccine development and challenges

WR Luo, XM Wu, W Wang, JL Yu, QQ Chen… - Microbial …, 2022 - Elsevier
The ongoing global pandemic of novel coronavirus pneumonia (COVID-19) caused by the
SARS-CoV-2 has a significant impact on global health and economy system. In this context …

Geographical prevalence of SARS-CoV-2 variants, August 2020 to July 2021

WS Chan, YM Lam, JHY Law, TL Chan, ESK Ma… - Scientific Reports, 2022 - nature.com
We extracted one-year genomic data (August 2020–July 2021) from GISAID EpiCoV™
database and estimated monthly proportions of 11 SARS-CoV-2 variants in various …

Characteristics of COVID-19 breakthrough infections among vaccinated individuals and associated risk factors: A systematic review

S Gopinath, A Ishak, N Dhawan, S Poudel… - Tropical medicine and …, 2022 - mdpi.com
We sought to assess breakthrough SARS-CoV-2 infections in vaccinated individuals by
variant distribution and to identify the common risk associations. The PubMed, Web of …