Association of VEGF promoter polymorphisms with gastrointestinal tract cancer risk and therapy response: a systematic review

D Mahajan, V Sambyal, K Guleria - Egyptian Journal of Medical Human …, 2025 - Springer
Background Gastrointestinal tract (GIT) cancers are the most lethal cancers with a high
incidence and poor prognosis. Vascular endothelial growth factor (VEGF) glycoprotein plays …

Vascular endothelial growth factor–2578C/A polymorphism and colorectal cancer risk: A meta-analysis

L Wang, S Ji, Z Cheng - Journal of Research in Medical Sciences, 2015 - journals.lww.com
Background: The effects of the vascular endothelial growth factor (VEGF) gene− 2578C/A
polymorphism on colorectal cancer (CRC) risk have been investigated in some studies; …

Impact of VEGFA promoter polymorphisms on esophageal cancer risk in North-West Indians: a case-control study

K Guleria, S Kaur, D Mahajan, V Sambyal, M Sudan… - Genes & Genomics, 2022 - Springer
Background Angiogenesis play a critical role in the development and progression of tumors
in solid tumors. Vascular endothelial growth factor (VEGF) is one of the most important …

VEGF Gene Polymorphisms and Susceptibility to Colorectal Cancer

AT Jannuzzi, G Özhan, HT Yanar… - Genetic testing and …, 2015 - liebertpub.com
Aims: Colorectal cancer (CRC) is the third most common cancer in the world and its etiology
involves the interaction of genetic and environmental factors. New blood vessels form …

Investigation of vascular endothelial growth factor polymorphisms on risk, metastasis, laterality, and prognosis of colorectal cancer in Turkish subjects

M Cevik, E Namal, N Dinc-Sener… - Genetic Testing and …, 2022 - liebertpub.com
Objectives: Tumor angiogenesis is known to support the spread and invasion of tumor cells,
allow distant organ metastasis and to result in poorer prognoses and increased mortality …

Vascular Endothelial Growth Factor (VEGF) Gene Polymorphisms and Colorectal Cancer: A Meta-Analysis of Epidemiologic Studies

Z Zhao, C Ba, W Wang, X Wang, R Xue… - Genetic testing and …, 2012 - liebertpub.com
Background: Studies investigating the association between vascular endothelial growth
factor (VEGF) polymorphisms and colorectal cancer (CRC) risk report conflicting results. To …

Interplay between 3′-UTR polymorphisms in the vascular endothelial growth factor (VEGF) gene and metabolic syndrome in determining the risk of colorectal cancer …

YJ Jeon, JW Kim, HM Park, HG Jang, JO Kim, J Oh… - BMC cancer, 2014 - Springer
Background Polymorphisms in angiogenesis-related genes and metabolic syndrome (MetS)
risk factors play important roles in cancer development. Moreover, recent studies have …

VEGF-2578C/A, -460T/C Polymorphisms and Gastrointestinal Tract Cancer Risk: An Updated Meta-Analysis

D Mahajan, V Sambyal, MS Uppal… - Genetic Testing and …, 2024 - liebertpub.com
Functional polymorphisms in the vascular endothelial growth factor (VEGF) alter the
susceptibility toward different gastrointestinal tract (GIT) cancers. In this study, we explored …

[HTML][HTML] Association of the vascular endothelial growth factor‑2578C/A polymorphism with cancer risk: A meta‑analysis update

Q Chen, Z Zhou, L Shan, Y Hua… - Biomedical …, 2014 - spandidos-publications.com
The vascular endothelial growth factor (VEGF)‑2578C/A polymorphism has been previously
reported to be associated with cancer risk; however, the results have been controversial …

A microRNA binding site polymorphism in the 3′ UTR region of VEGF-A gene modifies colorectal cancer risk based on ethnicity: a meta-analysis

SS Kontham, CEJ Walter, ZS Shankaran… - Journal of the Egyptian …, 2022 - Springer
Background Vascular endothelial growth factor A (VEGF-A) plays an integral role in
angiogenesis by contributing to growth, development, and metastasis of solid tumors …