Current trends in toxicity assessment of herbal medicines: A narrative review

A Jităreanu, A Trifan, M Vieriu, IC Caba, I Mârțu… - Processes, 2022 - mdpi.com
Even in modern times, the popularity level of medicinal plants and herbal medicines in
therapy is still high. The World Health Organization estimates that 80% of the population in …

Can natural products targeting EMT serve as the future anticancer therapeutics?

S Anwar, JA Malik, S Ahmed, VA Kameshwar, J Alanazi… - Molecules, 2022 - mdpi.com
Cancer is the leading cause of death and has remained a big challenge for the scientific
community. Because of the growing concerns, new therapeutic regimens are highly …

Assessment of the Phytochemical Profile, Antioxidant Capacity, and Hepatoprotective Effect of Andrographis paniculata against CCl4-Induced Liver Dysfunction in …

SK Ali, HA Makeen, G Khuwaja, HA Alhazmi… - Medicina, 2023 - mdpi.com
Recent studies have highlighted the necessity to thoroughly evaluate medicinal plants due
to their therapeutic potential. The current study delves into the phytochemical profile …

Mechanistic role of quercetin as inhibitor for adenosine deaminase enzyme in rheumatoid arthritis: systematic review

A Atta, MM Salem, KS El-Said, TM Mohamed - Cellular & Molecular …, 2024 - Springer
Rheumatoid arthritis (RA) is an autoimmune disease involving T and B lymphocytes.
Autoantibodies contribute to joint deterioration and worsening symptoms. Adenosine …

[HTML][HTML] Nigella sativa L. seed extracts promote wound healing progress by activating VEGF and PDGF signaling pathways: An in vitro and in silico study

CP Palanisamy, P Alugoju, S Jayaraman… - …, 2023 - ncbi.nlm.nih.gov
Background: A significant area of clinical research is the development of natural wound
healing products and the management of chronic wounds. Healing wounds with medicinal …

Exploring for HPLC-MS/MS Profiles and Biological Activities of Different Extracts from Allium lycaonicum Siehe ex Hayek from Turkey Flora

S Yagi, Nilofar, G Zengin, E Yildiztugay, G Caprioli… - Foods, 2023 - mdpi.com
The present study was designed to determine the phenolic constituents, antioxidant, and
enzyme inhibition activities of aerial parts and bulbs of Allium lycaonicum (family …

Antiproliferative Activities and SwissADME Predictions of Physicochemical Properties of Carbonyl Group‐Modified Rotenone Analogues

RD Hernandez, FAF Genio, JR Casanova… - …, 2024 - Wiley Online Library
Rotenone is a naturally occurring compound shown to exhibit antiproliferative activity
against various cancer cell lines, indicating its potential as a lead anticancer agent …

Chemical characterization and biological abilities of Anthocleista djalonensis collected from two locations of Ivory Coast

KI Sinan, G Zengin, AI Uba, G Caprioli, S Angeloni… - eFood, 2023 - Wiley Online Library
In this study, the total phenolic and flavonoid contents, HPLC‐DAD detected
phytochemicals, antioxidant and enzyme inhibitory potential of methanolic and aqueous (as …

Novel Signposts on the road from natural sources to pharmaceutical applications: A combinative approach between LC-DAD-MS and offline LC-NMR for the …

S Sut, S Dall'Acqua, G Zengin, I Senkardes, AI Uba… - Plants, 2023 - mdpi.com
The members of the genus Hypericum have great potential to develop functional uses in
nutraceutical and pharmaceutical applications. With this in mind, we aimed to determine the …

Bridging the Gap: Exploring the Preclinical Potential of Pereskia grandifolia in Metabolic‐Associated Fatty Liver Disease

E Rodrigues Albuquerque… - Evidence‐Based …, 2023 - Wiley Online Library
Metabolic‐associated fatty liver disease (MAFLD) is a complex condition characterized by
steatosis and metabolic disturbances. Risk factors such as diabetes, cigarette smoking, and …