Follicle-stimulating hormone (FSH) plays fundamental roles in male and female fertility. FSH
is a heterodimeric glycoprotein expressed by gonadotrophs in the anterior pituitary. The …

The pubertal development onset is controlled by a network of genes that regulate the
gonadotropin releasing hormone (GnRH) pulsatile release and the subsequent increase of …

Nanoplastics (NPs) spread widely with water and air current, and they can accumulate in
aquatic organisms, even penetrating biofilms, which may cause persistent toxicity and …

Follicle-stimulating hormone (FSH) plays fundamental roles in male and female fertility. FSH
is a heterodimeric glycoprotein expressed by gonadotrophs in the anterior pituitary. The …

Reproductive function adjusts in response to environmental conditions in order to optimize
success. In humans, this plasticity includes age of pubertal onset, hormone levels and age at …

Simple Summary The reproduction of mammals is regulated by the hypothalamic-pituitary-
gonadal axis. Follicle stimulating hormone, as one of the gonadotropins secreted by the …

Puberty is programmed through a multifactorial gene network which works to activate the
pulsatile secretion of the gonadotropin releasing hormone (GnRH), and subsequently …

Genome-wide studies have demonstrated regulatory roles for diverse non-coding elements,
but their precise and interrelated functions have often remained enigmatic. Addressing the …

Gonadotropin-releasing hormone (GnRH) stimulates the expression of multiple genes in the
pituitary gonadotropes, most notably to induce synthesis of the gonadotropins, luteinizing …

GnRH governs reproduction by regulating pituitary gonadotropins. Unlike most vertebrates,
gnrh−/− zebrafish are fertile. To elucidate the role of the hypophysiotropic-Gnrh3 and other …