Major depression is a prevalent illness that increases the risk of several neurological
conditions. These include stroke, cardiovascular disease, and dementia including …

Alzheimer's disease (AD) is the most common cause of dementia, accounting for more than
50 million patients worldwide. Current evidence suggests the exact mechanism behind this …

Background Inflammasomes have been found to interact with the gut microbiota, and this
effect is associated with depression, but the mechanisms underlying this interaction have not …

Objective: Depression is associated with an increased risk of Alzheimer's disease. Research
has shown that the selective serotonin reuptake inhibitor (SSRI) citalopram decreases …

Astrocytes play multifaceted and vital roles in maintaining neurophysiological function of the
central nervous system by regulating homeostasis, increasing synaptic plasticity, and …

Alzheimer9s disease (AD) is characterized by progressive cognitive decline, increasingly
attributed to neuronal dysfunction induced by amyloid-β oligomers (AβOs). Although the …

Alzheimer's disease (AD) is the most common cause of dementia, affecting 35 million people
worldwide. One pathological feature of progressing AD is the loss of synapses. This is the …

Abstract The glucagon-like peptide-1 (GLP-1) was shown to have neuroprotective effects in
Alzheimer's disease (AD). However, the underlying mechanism remains elusive. Astrocytic …

Given the failure to develop disease-modifying therapies for Alzheimer's disease (AD),
strategies aiming at preventing or delaying the onset of the disease are being prioritized …

Neurons suffer detrimental effects from β‐amyloid toxicity in Alzheimer's disease. The
exercise hormone, irisin, is found to induce a neuroprotective gene program and facilitates …