Autophagy in healthy aging and disease
Autophagy is a fundamental cellular process that eliminates molecules and subcellular
elements, including nucleic acids, proteins, lipids and organelles, via lysosome-mediated …
elements, including nucleic acids, proteins, lipids and organelles, via lysosome-mediated …
Targeting autophagy in disease: established and new strategies
Macroautophagy/autophagy is an evolutionarily conserved pathway responsible for clearing
cytosolic aggregated proteins, damaged organelles or invading microorganisms …
cytosolic aggregated proteins, damaged organelles or invading microorganisms …
The SARS-coronavirus infection cycle: a survey of viral membrane proteins, their functional interactions and pathogenesis
NA Wong, MH Saier Jr - International journal of molecular sciences, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel epidemic
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …
[HTML][HTML] Metabolomics profiling of critically ill coronavirus disease 2019 patients: identification of diagnostic and prognostic biomarkers
Objectives: Coronavirus disease 2019 continues to spread rapidly with high mortality. We
performed metabolomics profiling of critically ill coronavirus disease 2019 patients to …
performed metabolomics profiling of critically ill coronavirus disease 2019 patients to …
Implications of the novel mutations in the SARS-CoV-2 genome for transmission, disease severity, and the vaccine development
H Akkiz - Frontiers in medicine, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of the
coronavirus disease 2019 (COVID-19), has been identified in China in late December 2019 …
coronavirus disease 2019 (COVID-19), has been identified in China in late December 2019 …
Viroporins: Structure, function, and their role in the life cycle of SARS-CoV-2
Viroporins are indispensable for viral replication. As intracellular ion channels they disturb
pH gradients of organelles and allow Ca 2+ flux across ER membranes. Viroporins interact …
pH gradients of organelles and allow Ca 2+ flux across ER membranes. Viroporins interact …
The interplay between emerging human coronavirus infections and autophagy
Z Zhao, K Lu, B Mao, S Liu, M Trilling… - Emerging microbes & …, 2021 - Taylor & Francis
Following outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) and the
Middle East respiratory syndrome coronavirus (MERS-CoV) in 2002 and 2012, respectively …
Middle East respiratory syndrome coronavirus (MERS-CoV) in 2002 and 2012, respectively …
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms
We need to effectively combine the knowledge from surging literature with complex datasets
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
Role of endolysosomes in severe acute respiratory syndrome coronavirus-2 infection and coronavirus disease 2019 pathogenesis: implications for potential …
N Khan, X Chen, JD Geiger - Frontiers in pharmacology, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an enveloped, single-
stranded RNA virus. Humans infected with SARS-CoV-2 develop a disease known as …
stranded RNA virus. Humans infected with SARS-CoV-2 develop a disease known as …
Immunomodulatory effects of azithromycin revisited: potential applications to COVID-19
The rapid advancement of the COVID-19 pandemic has prompted an accelerated pursuit to
identify effective therapeutics. Stages of the disease course have been defined by viral …
identify effective therapeutics. Stages of the disease course have been defined by viral …