Working memory and executive function decline across normal aging, mild cognitive impairment, and Alzheimer's disease

AM Kirova, RB Bays, S Lagalwar - BioMed research …, 2015 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disease marked by deficits in
episodic memory, working memory (WM), and executive function. Examples of executive …

Neural dedifferentiation in the aging brain

JD Koen, MD Rugg - Trends in cognitive sciences, 2019 - cell.com
Many cognitive abilities decline with age even in the absence of detectable pathology.
Recent evidence indicates that age-related neural dedifferentiation, operationalized in terms …

Brain structure and cognitive ability in healthy aging: a review on longitudinal correlated change

J Oschwald, S Guye, F Liem, P Rast, S Willis… - Reviews in the …, 2019 - degruyter.com
Little is still known about the neuroanatomical substrates related to changes in specific
cognitive abilities in the course of healthy aging, and the existing evidence is predominantly …

Reorganization of brain networks in aging: a review of functional connectivity studies

R Sala-Llonch, D Bartrés-Faz, C Junqué - Frontiers in psychology, 2015 - frontiersin.org
Healthy aging (HA) is associated with certain declines in cognitive functions, even in
individuals that are free of any process of degenerative illness. Functional magnetic …

The efficacy of cognitive intervention in mild cognitive impairment (MCI): a meta-analysis of outcomes on neuropsychological measures

DS Sherman, J Mauser, M Nuno, D Sherzai - Neuropsychology review, 2017 - Springer
Cognitive training in MCI may stimulate pre-existing neural reserves or recruit neural
circuitry as “compensatory scaffolding” prompting neuroplastic reorganization to meet task …

Functional and/or structural brain changes in response to resistance exercises and resistance training lead to cognitive improvements–a systematic review

F Herold, A Törpel, L Schega, NG Müller - European Review of Aging and …, 2019 - Springer
Background During the aging process, physical capabilities (eg, muscular strength) and
cognitive functions (eg, memory) gradually decrease. Regarding cognitive functions …

Cognitive involvement in balance, gait and dual-tasking in aging: a focused review from a neuroscience of aging perspective

KZH Li, L Bherer, A Mirelman, I Maidan… - Frontiers in …, 2018 - frontiersin.org
A substantial corpus of evidence suggests that the cognitive involvement in postural control
and gait increases with aging. A large portion of such studies were based on dual-task …

Dynamics of cognitive control: Theoretical bases, paradigms, and a view for the future

G Gratton, P Cooper, M Fabiani, CS Carter… - …, 2018 - Wiley Online Library
Cognitive control (with the closely related concepts of attention control and executive
function) encompasses the collection of processes that are involved in generating and …

Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity

DR Seals, JN Justice, TJ LaRocca - The Journal of physiology, 2016 - Wiley Online Library
Most nations of the world are undergoing rapid and dramatic population ageing, which
presents great socio‐economic challenges, as well as opportunities, for individuals, families …

Defining cognitive reserve and implications for cognitive aging

C Pettigrew, A Soldan - Current neurology and neuroscience reports, 2019 - Springer
Abstract Purpose of Review The aim of this review is to summarize current conceptual
models of cognitive reserve (CR) and related concepts and to discuss evidence for these …