The insulin-like growth factors are major regulators of growth and development in mammals
and their presence in lower vertebrates suggests that they played a similarly fundamental …

The growth hormone (GH)/insulin-like growth factor (IGF) system plays an important role in
renal development, growth, function and pathophysiology. IGF-I has been associated with …

To gain a comprehensive understanding of the molecular mechanisms underlying the
effects of dietary protein on alternations in physiologic and pathologic status, the GeneChip …

The effects of dietary restriction of a single essential amino acid (EAA) on insulin-like growth
factor-I (IGF-I) and IGF-binding protein (IGFBP)-1 were investigated in rats. Rats were fed …

We previously reported that a low-protein diet caused animals to develop fatty liver
containing a high level of triglycerides (TG), similar to the human nutritional disorder …

Fatty liver impairs liver function and reduces productivity in dairy cows. Our previous in vivo
findings demonstrated that branched-chain amino acids (BCAA) or branched-chain ketoacid …

Human studies suggest that excessive energy intake and obesity may influence prostate
cancer progression. Rodent experiments demonstrate that diet restriction attenuates tumor …

The response of canine insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs)
to moderate nutritional restriction followed by refeeding has not previously been studied in …

To investigate the molecular mechanisms of increased transcription of the insulin-like growth
factor-binding protein-1 (IGFBP-1) gene in dietary protein-deprived animals, the cis-acting …

Nutrients serve not only as structural components of the body and its metabolic webs but
also as regulators of the expression of genes whose products are cell components. In turn …