Methods We conducted a systematic review and metanalysis according to PRISMA
guidelines searching on PubMed/Medline, Cochrane Database, and Scopus libraries and …

The increased incidence of osteoarthritis (OA), particularly knee and hip OA, and
osteoporosis (OP), owing to population aging, have escalated the medical expense burden …

Osteoarthritis (OA) is a debilitating joint disease characterized by progressive cartilage
degeneration, with no available disease-modifying therapy. OA is driven by pathological …

Patients with depression exhibit reduced bone mineral density (BMD). We previously
reported that the new antidepressant arketamine improved the reduced BMD seen in …

An association between psychiatric medications and falls and fractures in people taking
them has been demonstrated, but which class or medication leads to the greatest risk of falls …

Introduction Mental disorders and psychotropic medications are known to increase the risk
of osteoporosis and fractures. However, current evidence is mostly limited to studies that …

Objectives We assessed skeletal microstructure and stiffness in proton pump inhibitor (PPI)
users compared to non-users with high resolution peripheral quantitative computed …

Introduction Osteoporosis, a significant public health concern, affects millions of adult
women globally, leading to increased morbidity and fracture risk. Antidepressant use …

BACKGROUND Hip fracture in the elderly is a worldwide medical problem. New-onset
depression after hip fracture has also received attention because of its increasing incidence …

Impaired fracture healing is of high clinical relevance, as up to 15% of patients with long-
bone fractures display non-unions. Fracture patients also include individuals treated with …