Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications

WZ Zhuang, YH Lin, LJ Su, MS Wu, HY Jeng… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …

Overcoming the Achilles' heel of photodynamic therapy

W Fan, P Huang, X Chen - Chemical Society Reviews, 2016 - pubs.rsc.org
Photodynamic therapy (PDT) has been applied to treat a wide range of medical conditions,
including wet age-related macular degeneration psoriasis, atherosclerosis, viral infection …

Magnetic nanoparticle facilitated drug delivery for cancer therapy with targeted and image‐guided approaches

J Huang, Y Li, A Orza, Q Lu, P Guo… - Advanced functional …, 2016 - Wiley Online Library
With rapid advances in nanomedicine, magnetic nanoparticles (MNPs) have emerged as a
promising theranostic tool in biomedical applications, including diagnostic imaging, drug …

[HTML][HTML] Exploring multi-element co-doped carbon dots as dual-mode probes for fluorescence/CT imaging

P Zhu, X Zhao, Q Zhu, X Han, Y Tang, S Liao… - Chemical Engineering …, 2023 - Elsevier
Osteosarcoma (OS), the most common pediatric malignant bone tumor, has been stagnant
in its current treatment status due to its highly heterogeneous, aggressive, and lethal nature …

Radiolabeling nanomaterials for multimodality imaging: New insights into nuclear medicine and cancer diagnosis

J Ge, Q Zhang, J Zeng, Z Gu, M Gao - Biomaterials, 2020 - Elsevier
Nuclear medicine imaging has been developed as a powerful diagnostic approach for
cancers by detecting gamma rays directly or indirectly from radionuclides to construct …

Positron emission tomography and nanotechnology: A dynamic duo for cancer theranostics

S Goel, CG England, F Chen, W Cai - Advanced drug delivery reviews, 2017 - Elsevier
Abstract Development of novel imaging probes for cancer diagnosis is critical for early
disease detection and management. The past two decades have witnessed a surge in the …

Massive intracellular biodegradation of iron oxide nanoparticles evidenced magnetically at single-endosome and tissue levels

F Mazuel, A Espinosa, N Luciani, M Reffay… - ACS …, 2016 - ACS Publications
Quantitative studies of the long-term fate of iron oxide nanoparticles inside cells, a
prerequisite for regenerative medicine applications, are hampered by the lack of suitable …

Biocompatible iron oxide nanoring-labeled mesenchymal stem cells: an innovative magnetothermal approach for cell tracking and targeted stroke therapy

H Liu, R Sun, L Wang, X Chen, G Li, Y Cheng, G Zhai… - ACS …, 2022 - ACS Publications
Labeling stem cells with magnetic nanoparticles is a promising technique for in vivo tracking
and magnetic targeting of transplanted stem cells, which is critical for improving the …

A 3D magnetic tissue stretcher for remote mechanical control of embryonic stem cell differentiation

V Du, N Luciani, S Richard, G Mary, C Gay… - Nature …, 2017 - nature.com
The ability to create a 3D tissue structure from individual cells and then to stimulate it at will
is a major goal for both the biophysics and regenerative medicine communities. Here we …

Tumor microenvironment-responsive nanohybrid for hypoxia amelioration with photodynamic and near-infrared II photothermal combination therapy

P Zhang, Q Wu, J Yang, M Hou, B Zheng, J Xu, Y Chai… - Acta Biomaterialia, 2022 - Elsevier
Phototherapy, particularly photothermal therapy (PTT) and photodynamic therapy (PDT), has
been widely investigated for tumor treatment. However, the limited tissue penetration depth …