For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

Phthalates are commonly used as plasticizers in the manufacturing of flexible polyvinyl
chloride products. Large production volumes of phthalates and their widespread use in …

Over 6 billion pounds per year of the estrogenic monomer bisphenol A (BPA) are used to
manufacture polycarbonate plastic products, in resins lining metal cans, in dental sealants …

Information concerning the fundamental mechanisms of action of both natural and
environmental hormones, combined with information concerning endogenous hormone …

This report is an overview of the current state of the science relative to environmental
endocrine disruption in humans, laboratory testing, and wildlife species. Background …

The assembly of the primordial follicles early in ovarian development and the subsequent
development and transition of the primordial follicle to the primary follicle are critical …

We have developed a relative binding affinity-serum modified access (RBA-SMA) assay to
determine the effect of serum on the access of xenoestrogens to estrogen receptors within …

On the basis of results of studies using high doses of estrogens, exposure to estrogen during
fetal life is known to inhibit prostate development. However, it is recognized in endocrinology …

The assembly of the developmentally arrested primordial follicle and the subsequent
transition of the primordial follicle to the primary follicle are critical processes in normal …

Over six-billion pounds per year of the monomer bisphenol A (BPA) are used to manufacture
polycarbonate plastic products, resins lining cans, dental sealants, and polyvinyl chloride …