Large-scale recombinant production of the SARS-CoV-2 proteome for high-throughput and structural biology applications

N Altincekic, SM Korn, NS Qureshi… - Frontiers in molecular …, 2021 - frontiersin.org
The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses
a severe threat to humanity and demands the redirection of scientific efforts and criteria to …

Comprehensive fragment screening of the SARS‐CoV‐2 proteome explores novel chemical space for drug development

H Berg, MA Wirtz Martin, N Altincekic… - Angewandte Chemie …, 2022 - Wiley Online Library
Abstract SARS‐CoV‐2 (SCoV2) and its variants of concern pose serious challenges to the
public health. The variants increased challenges to vaccines, thus necessitating for …

Theory and computation of nuclear shielding

T Kupka - 2020 - books.rsc.org
A review of the literature published from January to December 2019 on theoretical aspects
of nuclear magnetic shielding is presented. It covers both non-relativistic and relativistic …

[HTML][HTML] NMR spectroscopy spotlighting immunogenicity induced by COVID-19 vaccination to mitigate future health concerns

S Ali, Š Nedvědová, G Badshah, MS Afridi… - Current Research in …, 2022 - Elsevier
In this review, the disease and immunogenicity affected by COVID-19 vaccination at the
metabolic level are described considering the use of nuclear magnetic resonance (NMR) …

Despite the odds: formation of the SARS-CoV-2 methylation complex

A Matsuda, J Plewka, M Rawski, A Mourão… - Nucleic Acids …, 2024 - academic.oup.com
Coronaviruses modify their single-stranded RNA genome with a methylated cap during
replication to mimic the eukaryotic mRNAs. The capping process is initiated by several …

NMR of proteins and nucleic acids

RA Atkinson - 2021 - books.rsc.org
A review of key publications from 2020, describing methodological developments and
research applications of NMR of proteins and nucleic acids. Particularly novel approaches …

NSP7, NSP8, NSP9, NSP10, NSP16, and NSP14

J Zhang - Optimization-based Molecular Dynamics Studies of …, 2023 - Springer
The optimized molecular structures of NSP7, NSP8, NSP9, NSP10, NSP10-NSP16 complex,
NSP16, NSP10-NSP14 complex, and NSP14 are studied, and their basic structural …

[PDF][PDF] Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications

H Schwalbe, M Hengesbach, A Schlundt - pure-oai.bham.ac.uk
The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses
a severe threat to humanity and demands the redirection of scientific efforts and criteria to …