[HTML][HTML] Short chain fatty acids, a possible treatment option for autoimmune diseases

F Golpour, M Abbasi-Alaei, F Babaei… - Biomedicine & …, 2023 - Elsevier
Gut microbiota can interact with the immune system through its metabolites. Short-chain fatty
acids (SCFAs), as one of the most abundant metabolites of the resident gut microbiota play …

[HTML][HTML] Protective role of butyrate in obesity and diabetes: New insights

A Mayorga-Ramos, C Barba-Ostria… - Frontiers in …, 2022 - frontiersin.org
Studies in human microbiota dysbiosis have shown that short-chain fatty acids (SCFAs) like
propionate, acetate, and particularly butyrate, positively affect energy homeostasis …

[HTML][HTML] Sodium butyrate ameliorates diabetic retinopathy in mice via the regulation of gut microbiota and related short-chain fatty acids

Y Huang, Z Wang, B Ye, JH Ma, S Ji, W Sheng… - Journal of Translational …, 2023 - Springer
Background Diabetic retinopathy (DR) development is associated with disturbances in the
gut microbiota and related metabolites. Butyric acid is one of the short-chain fatty acids …

[HTML][HTML] Resistant starch as a dietary intervention to limit the progression of diabetic kidney disease

AM Drake, MT Coughlan, CT Christophersen… - Nutrients, 2022 - mdpi.com
Diabetes is the leading cause of kidney disease, and as the number of individuals with
diabetes increases there is a concomitant increase in the prevalence of diabetic kidney …

The implication of short-chain fatty acids in obesity and diabetes

O Anachad, A Taouil, W Taha, F Bennis… - Microbiology …, 2023 - journals.sagepub.com
Evidence indicates that short-chain fatty acids (SCFAs) generated from the gut microbiota
play crucial roles in host metabolism. They contribute to metabolic regulation and energy …

[HTML][HTML] Targeted delivery of butyrate improves glucose homeostasis, reduces hepatic lipid accumulation and inflammation in db/db mice

SS Pedersen, M Prause, C Sørensen, J Størling… - International Journal of …, 2023 - mdpi.com
Butyrate produced by the gut microbiota has beneficial effects on metabolism and
inflammation. Butyrate-producing bacteria are supported by diets with a high fiber content …

Butyrate Prevents the Pathogenic Anemia‐Inflammation Circuit by Facilitating Macrophage Iron Export

P Xiao, X Cai, Z Zhang, K Guo, Y Ke, Z Hu… - Advanced …, 2024 - Wiley Online Library
Most patients with inflammatory bowel disease (IBD) develop anemia, which is attributed to
the dysregulation of iron metabolism. Reciprocally, impaired iron homeostasis also …

Harnessing and delivering microbial metabolites as therapeutics via advanced pharmaceutical approaches

LM Williams, S Cao - Pharmacology & Therapeutics, 2024 - Elsevier
Microbial metabolites have emerged as key players in the interplay between diet, the gut
microbiome, and host health. Two major classes, short-chain fatty acids (SCFAs) and …

[HTML][HTML] Nutritional Strategies against Diabetic Nephropathy: Insights from Animal Studies and Human Trials

J Zhou, N Franceschini, WHD Townley-Tilson… - Nutrients, 2024 - mdpi.com
Diabetic nephropathy (DN), defined as continuously elevated urinary albumin and a
diminished estimated glomerular filtration rate, is a serious complication of both type 1 …

[HTML][HTML] The Effect of Microbiome-Modulating Agents (MMAs) on Type 1 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Y Zhang, A Huang, J Li, W Munthali, S Cao, UMP Putri… - Nutrients, 2024 - mdpi.com
Gut microbiome-modulating agents (MMAs), including probiotics, prebiotics, postbiotics, and
synbiotics, are shown to ameliorate type 1 diabetes (T1D) by restoring the microbiome from …