Soft biological tissues are complex materials with a large structural variety, with differences
in behavior, but with some common characteristics. Skin is an archetypal soft tissue which …

Coronary atherosclerosis is the major cause of mortality and disability in developed nations.
A deeper understanding of mechanical properties of coronary arteries and hence their …

Fundamental to developing a deeper understanding of pathophysiological remodeling in
mitral valve (MV) disease is the development of an accurate tissue-level constitutive model …

The mechanical loading-deformation relation of elastin and collagen fibril bundles is
fundamental to understanding the microstructural properties of tissue. Here, we use …

The microstructure of arteries, consisting, in particular, of collagen, elastin, and vascular
smooth muscle cells, plays a very significant role in their biomechanical response during a …

Cardiovascular diseases (CVDs) are the leading cause of death in the western world. With
the current development of clinical diagnostics to more accurately measure the extent and …

This work presents a novel microstructurally-based, multi-scale model describing the
passive behaviour of skeletal muscle tissue. The model is based on the detailed description …

Introduction Aim of this study is to validate some constitutive models by assessing their
capabilities in describing and predicting uniaxial and biaxial behavior of porcine aortic …

Soft tissues account for a major fraction of the body volume and mass. They are present in
all non-skeletal organs, being responsible for protecting the body, maintaining internal …

The microstructural deformation-mechanical loading relation of the blood vessel wall is
essential for understanding the overall mechanical behavior of vascular tissue in health and …