Toxoplasma gondii is an obligate intracellular protozoan parasite which is a significant
human and veterinary pathogen. Other members of the phylum Apicomplexa are also …

One of the hallmarks of the parasitic phylum of Apicomplexa is the presence of highly
specialised, apical secretory organelles, called the micronemes and rhoptries that play …

Apicomplexan parasites cause persistent mortality and morbidity worldwide through
diseases including malaria, toxoplasmosis, and cryptosporidiosis. Ca 2+ signaling pathways …

The alveolate superphylum includes many free-living and parasitic organisms, which are
united by the presence of alveolar sacs lying proximal to the plasma membrane, providing …

Parasites of the genus Plasmodium, the etiological agent of malaria, are transmitted through
the bite of anopheline mosquitoes, which deposit sporozoites into the host skin. Sporozoites …

Toxoplasma gondii is an obligate intracellular apicomplexan parasite that infects warm-
blooded vertebrates, including humans. Asexual reproduction in T. gondii allows it to switch …

Malaria is caused by four species of apicomplexan protozoa belonging to the genus
Plasmodium. These parasites possess a specialized collection of secretory organelles …

The organelle paralogy hypothesis (OPH) aims to explain the evolution of non-
endosymbiotically derived organelles. It predicts that lineage-specific pathways or …

The importance of Ca2+-signaling for many subcellular processes is well established in
higher eukaryotes, whereas information about protozoa is restricted. Recent genome …

Although it is generally accepted that nuclear architecture is an important determinant of
nuclear activity, it is not clear whether cytoplasmic events, such as transcript localization and …