Current view on phytoplasma genomes and encoded metabolism

M Kube, J Mitrovic, B Duduk, R Rabus… - The Scientific World …, 2012 - Wiley Online Library
Phytoplasmas are specialised bacteria that are obligate parasites of plant phloem tissue and
insects. These bacteria have resisted all attempts of cell‐free cultivation. Genome research …

[HTML][HTML] Mycoplasmas and cancer: focus on nucleoside metabolism

JV Voorde, J Balzarini, S Liekens - EXCLI journal, 2014 - ncbi.nlm.nih.gov
The standard of care for patients suffering cancer often includes treatment with nucleoside
analogues (NAs). NAs are internalized by cell-specific nucleobase/nucleoside transporters …

A Genome-Scale Metabolic Reconstruction of Mycoplasma genitalium, iPS189

PF Suthers, MS Dasika, VS Kumar… - PLoS computational …, 2009 - journals.plos.org
With a genome size of∼ 580 kb and approximately 480 protein coding regions, Mycoplasma
genitalium is one of the smallest known self-replicating organisms and, additionally, has …

New insights on the biology of swine respiratory tract mycoplasmas from a comparative genome analysis

FM Siqueira, CE Thompson, VG Virginio… - BMC genomics, 2013 - Springer
Abstract Background Mycoplasma hyopneumoniae, Mycoplasma flocculare and
Mycoplasma hyorhinis live in swine respiratory tracts. M. flocculare, a commensal bacterium …

Mycoplasma bovis 5′-nucleotidase is a virulence factor conferring mammary fitness in bovine mastitis

AE Gelgie, P Schneider, C Citti, E Dordet-Frisoni… - PLoS …, 2024 - journals.plos.org
Nucleases and 5′ nucleotidase (5′-NT) play essential roles in cell biology and are often
associated with bacterial virulence. In Mycoplasma spp., which have limited metabolic …

Integration of metabolomics and existing omics data reveals new insights into phytoplasma-induced metabolic reprogramming in host plants

Y Tan, Q Li, Y Zhao, H Wei, J Wang, CJ Baker, Q Liu… - PLoS …, 2021 - journals.plos.org
Phytoplasmas are cell wall-less bacteria that induce abnormal plant growth and various
diseases, causing severe economic loss. Phytoplasmas are highly dependent on nutrients …

Comparative metabolomics of Mycoplasma bovis and Mycoplasma gallisepticum reveals fundamental differences in active metabolic pathways and suggests novel …

Y Masukagami, DP De Souza, S Dayalan, C Bowen… - …, 2017 - Am Soc Microbiol
Mycoplasmas are simple, but successful parasites that have the smallest genome of any free-
living cell and are thought to have a highly streamlined cellular metabolism. Here, we have …

Complete Genome Sequence of Mycoplasma suis and Insights into Its Biology and Adaption to an Erythrocyte Niche

AMS Guimaraes, AP Santos, P SanMiguel, T Walter… - PloS one, 2011 - journals.plos.org
Mycoplasma suis, the causative agent of porcine infectious anemia, has never been cultured
in vitro and mechanisms by which it causes disease are poorly understood. Thus, the …

Selection-driven cost-efficiency optimization of transcripts modulates gene evolutionary rate in bacteria

EA Seward, S Kelly - Genome biology, 2018 - Springer
Background Most amino acids are encoded by multiple synonymous codons. However,
synonymous codons are not used equally, and this biased codon use varies between …

Phytoplasma genomes: evolution through mutually complementary mechanisms, gene loss and horizontal acquisition

Y Zhao, RE Davis, W Wei, J Shao… - Genomics of plant …, 2014 - Springer
Phytoplasmas are cell wall-less bacteria that inhabit phloem sieve cells of infected plants
and are transmitted by phloem-feeding insect vectors. Having descended from a Gram …