[HTML][HTML] Mitochondrial channels: ion fluxes and more

I Szabo, M Zoratti - Physiological reviews, 2014 - journals.physiology.org
The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

Venom Peptides, Polyphenols and Alkaloids: Are They the Next Antidiabetics That Will Preserve β-Cell Mass and Function in Type 2 Diabetes?

M Lodato, V Plaisance, V Pawlowski, M Kwapich… - Cells, 2023 - mdpi.com
Improvement of insulin secretion by pancreatic β-cells and preservation of their mass are the
current challenges that future antidiabetic drugs should meet for achieving efficient and long …

Neuroprotective and therapeutic effect of caffeine on the rat model of Parkinson's disease induced by rotenone

YA Khadrawy, AM Salem, KA El-Shamy… - Journal of Dietary …, 2017 - Taylor & Francis
The present study aimed to investigate the protective and therapeutic effects of caffeine on
rotenone-induced rat model of Parkinson's disease (PD). Rats were divided into control, PD …

Involvement of serotonergic, noradrenergic and dopaminergic systems in the antidepressant-like effect of ginsenoside Rb1, a major active ingredient of Panax …

GL Wang, ZM He, HY Zhu, YG Gao, Y Zhao… - Journal of …, 2017 - Elsevier
Abstract Ethnopharmacology relevance Ginsenoside Rb1, a 20 (S)-protopanaxadiol, is a
major active ingredient of Panax ginseng CA Meyer, which as the King of Chinese herbs …

Evaluation of antioxidant and anti-inflammatory efficacy of caffeine in rat model of neurotoxicity

EN Hosny, HG Sawie, ME Elhadidy… - Nutritional …, 2019 - Taylor & Francis
Objective: The present study aims to investigate the neuroprotective effect of caffeine against
aluminum chloride (AlCl3)-induced neurotoxicity in rats. Methods: Twenty-one male albino …

Activation of cGMP-dependent protein kinase stimulates cardiac ATP-sensitive potassium channels via a ROS/calmodulin/CaMKII signaling cascade

Y Chai, DM Zhang, YF Lin - PLoS One, 2011 - journals.plos.org
Background Cyclic GMP (cGMP)-dependent protein kinase (PKG) is recognized as an
important signaling component in diverse cell types. PKG may influence the function of …

Intracellular signalling mechanism responsible for modulation of sarcolemmal ATP‐sensitive potassium channels by nitric oxide in ventricular cardiomyocytes

DM Zhang, Y Chai, JR Erickson… - The Journal of …, 2014 - Wiley Online Library
Key points Both the ATP‐sensitive potassium (KATP) channel and the gaseous messenger
nitric oxide (NO) play fundamental roles in protecting the heart from injuries related to …

咖啡碱的生理功能及其作用机制

吴命燕, 范方媛, 梁月荣, 郑新强, 陆建良 - 茶叶科学, 2019 - tea-science.com
咖啡碱的生理功能及其作用机制The Physiological Functions of Caffeine and Their Related
Mechanisms Page 1 茶叶科学2010,30(4):235~242 Journal of Tea Science 收稿日期:2009-11-18 …

Addressing the Neuroprotective Actions of Coffee in Parkinson's Disease: An Emerging Nutrigenomic Analysis

LK Lee, NAR Mhd Rodzi - Antioxidants, 2022 - mdpi.com
Caffeine is one of the predominant dietary components and psychostimulants present in
coffee, a widely appreciated beverage. Corroborating epidemiological and laboratory …

Sulfonylurea receptor 1 contributes to the astrocyte swelling and brain edema in acute liver failure

AR Jayakumar, V Valdes, XY Tong… - Translational stroke …, 2014 - Springer
Astrocyte swelling (cytotoxic brain edema) is the major neurological complication of acute
liver failure (ALF), a condition in which ammonia has been strongly implicated in its etiology …