The safety of systemic Janus kinase inhibitors in atopic dermatitis: a systematic review and network meta-analysis
C Alves, A Penedones, D Mendes… - European Journal of …, 2022 - Springer
Purpose Janus kinase (JAK) inhibitors have been developed to treat moderate to severe
atopic dermatitis, but there is little evidence comparing the safety profile of these drugs. The …
atopic dermatitis, but there is little evidence comparing the safety profile of these drugs. The …
Comparison of adalimumab to other targeted therapies in rheumatoid arthritis: results from systematic literature review and meta-analysis
Few studies compared adalimumab to other targeted therapies in head-to-head randomized
clinical trials (RCTs) for rheumatoid arthritis (RA), but multiple comparisons are not …
clinical trials (RCTs) for rheumatoid arthritis (RA), but multiple comparisons are not …
A convolutional neural network with transfer learning for automatic discrimination between low and high-grade synovitis: a pilot study
Ultrasound-guided synovial tissue biopsy (USSB) may allow personalizing the treatment for
patients with inflammatory arthritis. To this end, the quantification of tissue inflammation in …
patients with inflammatory arthritis. To this end, the quantification of tissue inflammation in …
Preferable outcome of Janus kinase inhibitors for a group of difficult-to-treat rheumatoid arthritis patients: from the FIRST Registry
S Ochi, K Sonomoto, S Nakayamada… - Arthritis Research & …, 2022 - Springer
Backgrounds Treatment of difficult-to-treat rheumatoid arthritis (D2T RA) is one of the
greatest unmet needs in rheumatology. This study aims to find out preferable treatment …
greatest unmet needs in rheumatology. This study aims to find out preferable treatment …
Evolution of rheumatoid-arthritis-associated interstitial lung disease in patients treated with JAK inhibitors: a retrospective exploratory study
V Venerito, A Manfredi, A Carletto… - Journal of Clinical …, 2023 - mdpi.com
Background: The aim of this multicenter retrospective study was to investigate the
effectiveness and safety of the available JAK-inhibitors (JAKi) in patients with rheumatoid …
effectiveness and safety of the available JAK-inhibitors (JAKi) in patients with rheumatoid …
A machine learning approach for predicting sustained remission in rheumatoid arthritis patients on biologic agents
Background Despite several studies having identified factors associated with successful
treatment outcomes in rheumatoid arthritis (RA), there is a lack of accurate predictive models …
treatment outcomes in rheumatoid arthritis (RA), there is a lack of accurate predictive models …
Эффективность и безопасность тофацитиниба при иммуновоспалительных ревматических заболеваниях (часть I)
ЕЛ Насонов, АС Авдеева, АМ Лила - Научно-практическая …, 2020 - cyberleninka.ru
Расшифровка механизмов патогенеза иммуновоспалительных ревматических
заболеваний (ИВРЗ) в сочетании с разработкой широкого спектра генно-инженерных …
заболеваний (ИВРЗ) в сочетании с разработкой широкого спектра генно-инженерных …
Identification of a rule to predict response to sarilumab in patients with rheumatoid arthritis using machine learning and clinical trial data
M Rehberg, C Giegerich, A Praestgaard… - Rheumatology and …, 2021 - Springer
Introduction In rheumatoid arthritis, time spent using ineffective medications may lead to
irreversible disease progression. Despite availability of targeted treatments, only a minority …
irreversible disease progression. Despite availability of targeted treatments, only a minority …
ZAP-70 regulates autoimmune arthritis via alterations in T cell activation and apoptosis
T cells play an essential role in the pathogenesis of both human rheumatoid arthritis (RA)
and its murine models. A key molecule in T cell activation is ZAP-70, therefore we aimed to …
and its murine models. A key molecule in T cell activation is ZAP-70, therefore we aimed to …
Topical Janus kinase inhibitors in atopic dermatitis: a safety network meta-analysis
C Alves, A Penedones, D Mendes… - International Journal of …, 2023 - Springer
Abstract Background Topical Janus kinase (JAK) inhibitors are being developed for the
treatment of mild to moderate atopic dermatitis. However, comparative evidence on their …
treatment of mild to moderate atopic dermatitis. However, comparative evidence on their …