Pituitary disease is associated with increased mortality predominantly due to vascular
disease. Control of cortisol secretion and GH hypersecretion (and cardiovascular risk factor …

Background: Obesity is characterized by chronic inflammation, immune dysregulation, and
alteration of gene expression, associated with type 2 diabetes mellitus and cardiovascular …

Objective In patients with active Cushing's syndrome (CS), cardiac structural and functional
changes have been described in a limited number of patients. It is unknown whether these …

Background: Patients with Cushing's syndrome have left ventricular (LV) hypertrophy and
dysfunction on echocardiography, but echo-based measurements may have limited …

Objectives Sustained hypercortisolism impacts cardiac function, and, indeed, cardiac
disease is one of the major determinants of mortality in patients with Cushing's syndrome …

Abstract Objective Active Cushing's syndrome (CS) is associated with cardiomyopathy,
characterized by myocardial structural, and ultrastructural abnormalities. The extent of …

Background Cushing's disease is a rare condition associated with a high cardiovascular risk
and hypercortisolemia-related hemodynamic dysfunction, the extent of which can be …

Background: Myocardial performance index (MPI), or Tei index, is an indicator of systolic
and diastolic myocardial function. MPI increases in case of cardiac dysfunction; however …

Cushing's syndrome (CS) is a severe chronic and systemic condition caused by
endogenous or exogenous excess of glucocorticoids, associated with increased morbidity …

Background Cushing disease (CD) may lead to accelerated cardiovascular remodeling and
increased mortality. There are suspected differences in the mechanism of cardiovascular …