[HTML][HTML] Nanoformulations of curcumin: an emerging paradigm for improved remedial application

M Gera, N Sharma, M Ghosh, SJ Lee, T Min, T Kwon… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Curcumin is a natural polyphenol and essential curcuminoid derived from the rhizome of the
medicinal plant Curcuma longa (L.) is universally acknowledged as “Wonder drug of life”. It …

Dietary phytochemicals in colorectal cancer prevention and treatment: A focus on the molecular mechanisms involved

S Afrin, F Giampieri, M Gasparrini… - Biotechnology …, 2020 - Elsevier
Worldwide, colorectal cancer (CRC) remains a major cancer type and leading cause of
death. Unfortunately, current medical treatments are not sufficient due to lack of effective …

The role of curcumin in modulating colonic microbiota during colitis and colon cancer prevention

RMT McFadden, CB Larmonier… - Inflammatory bowel …, 2015 - academic.oup.com
Background Intestinal microbiota influences the progression of colitis-associated colorectal
cancer. With diet being a key determinant of the gut microbial ecology, dietary interventions …

Effect of curcumin supplementation on physiological fatigue and physical performance in mice

WC Huang, WC Chiu, HL Chuang, DW Tang, ZM Lee… - Nutrients, 2015 - mdpi.com
Curcumin (CCM) is a well-known phytocompound and food component found in the spice
turmeric and has multifunctional bioactivities. However, few studies have examined its …

Analgesic efficacy and safety of curcuminoids in clinical practice: a systematic review and meta-analysis of randomized controlled trials

A Sahebkar, Y Henrotin - Pain medicine, 2016 - academic.oup.com
Background. Curcuminoids are natural products with potent anti-inflammatory and
antioxidant properties. There have been a number of reports on the analgesic effects of …

Curcumin induces apoptosis and cell cycle arrest via the activation of reactive oxygen species–independent mitochondrial apoptotic pathway in Smad4 and p53 …

A Agarwal, A Kasinathan, R Ganesan… - Nutrition Research, 2018 - Elsevier
Curcumin is a natural dietary polyphenol compound that has various pharmacological
activities such as antiproliferative and cancer-preventive activities on tumor cells. Indeed, the …

Toward regulatory effects of curcumin on transforming growth factor-beta across different diseases: a review

M Ashrafizadeh, A Zarrabi, K Hushmandi… - Frontiers in …, 2020 - frontiersin.org
Immune response, proliferation, migration and angiogenesis are juts a few of cellular events
that are regulated by transforming growth factor-β (TGF-β) in cells. A number of studies have …

Cucurmin, anticancer, & antitumor perspectives: A comprehensive review

M Imran, A Ullah, F Saeed, M Nadeem… - Critical reviews in …, 2018 - Taylor & Francis
Cucurmin, a naturally yellow component isolated from turmeric, ability to prevent various life-
style related disorders. The current review article mainly emphasizes on different anticancer …

The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53

C Hu, M Zhang, N Moses, C Hu, L Polin, W Chen… - Cell death & …, 2020 - nature.com
Abstract Ubiquitin-specific peptidase 10 (USP10) stabilizes both tumor suppressors and
oncogenes in a context-dependent manner. However, the nature of USP10's role in non …

Fibroblast-like synoviocytes-dependent effector molecules as a critical mediator for rheumatoid arthritis: current status and future directions

R Ganesan, M Rasool - International reviews of immunology, 2017 - Taylor & Francis
Rheumatoid arthritis (RA) is a systemic-autoimmune-mediated disease characterized by
synovial hyperplasia and progressive destruction of joint. Currently available biological …