Shear stress and endothelial mechanotransduction in trauma patients with hemorrhagic shock: hidden coagulopathy pathways and novel therapeutic strategies

A Chalkias - International Journal of Molecular Sciences, 2023 - mdpi.com
Massive trauma remains a leading cause of death and a global public health burden. Post-
traumatic coagulopathy may be present even before the onset of resuscitation, and …

Design of artificial vascular devices: Hemodynamic evaluation of shear-induced thrombogenicity

T Feaugas, G Newman, ST Calzuola… - Frontiers in …, 2023 - frontiersin.org
Blood-circulating devices such as oxygenators have offered life-saving opportunities for
advanced cardiovascular and pulmonary failures. However, such systems are limited in the …

A computational study of fibrinogen-induced alteration in microvascular blood flow in COVID-19

K Han, W Zhou, S Ma, S Wang, X Qi, L Guo… - The European Physical …, 2023 - Springer
Patients infected with COVID-19 may experience significant and long-lasting changes in the
mechanical and rheological properties of their blood cells, leading to microvascular …

Ingenious Microfluidic-Microwave integrated biosensor for cell sorting and concentration detection of mixed white blood cells and yeasts solution

YB Li, YX Wang, S Yang, QL Chen, ZH Li… - Chemical Engineering …, 2025 - Elsevier
We propose an integrated biosensor that combines microwave sensor with microfluidic chip
for sorting and detection of biological cells. The microwave sensor consists of resonator and …

Effect of micro-vessel stenosis severity and hematocrit level on red blood cell dynamics and platelet margination: A numerical study

A Elhanafy, Y Abuouf, S Elsagheer, S Ookawara… - International Journal of …, 2024 - Elsevier
Understanding many micro-vascular diseases is aided by examining the dynamical
behavior of blood cells. For instance, micro-vascular stenosis significantly influences the …

Platelet Adhesion and Activation in an ECMO Thrombosis‐on‐a‐Chip Model

T Goh, L Gao, J Singh, R Totaro, R Carey… - Advanced …, 2024 - Wiley Online Library
Use of extracorporeal membrane oxygenation (ECMO) for cardiorespiratory failure remains
complicated by blood clot formation (thrombosis), triggered by biomaterial surfaces and flow …

Unraveling the motion and deformation characteristics of red blood cells in a deterministic lateral displacement device

S Liu, S Chen, L Xiao, K Zhang, Y Qi, H Li… - Computers in Biology …, 2024 - Elsevier
Abstract Deterministic Lateral Displacement (DLD) device has gained widespread
recognition and trusted for filtering blood cells. However, there remains a crucial need to …

Platelet margination dynamics in blood flow: The role of lift forces and red blood cells aggregation

M Dynar, H Ez-Zahraouy, C Misbah, M Abbasi - Physical Review Fluids, 2024 - APS
Homeostasis plays a critical role in maintaining the delicate balance between preventing
excessive bleeding and enabling clot formation during injuries. One pivotal aspect of …

Real-time prediction of heparin concentration in blood extracorporeal circulation by relaxation time distribution (RTD)

S Ueno, D Kawashima, K Matsuura, H Obara… - …, 2025 - Elsevier
Heparin concentration c in a blood extracorporeal circulation has been real-timely predicted
based on the relaxation strength Δ ε m at relaxation frequency fm extracted by relaxation …

The Relation of Calculated Plasma Volume Status to Sublingual Microcirculatory Blood Flow and Organ Injury

E Laou, N Papagiannakis, N Ntalarizou… - Journal of Personalized …, 2023 - mdpi.com
Background: The calculated plasma volume status (cPVS) was validated as a surrogate of
intravascular filling. The aim of this study is to assess the cPVS in relation to sublingual …