The hepatic immune system is constantly exposed to a massive load of harmless dietary and
commensal antigens, to which it must remain tolerant. Immune tolerance in the liver is …

The emergence of SARS-CoV-2 variants of concern with progressively increased
transmissibility between humans is a threat to global public health. The Omicron variant of …

Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …

Mucosal-associated invariant T cells or MAIT cells are an abundant cell type in humans and
especially so in the liver. MAIT cells are a subset of T lymphocytes that sit at a bridge …

Liver fibrosis is the common response to chronic liver injury, and leads to cirrhosis and its
complications. Persistent inflammation is a driving force of liver fibrosis progression …

Mucosal-associated invariant T (MAIT) cells are resident T cells that express semi-invariant
TCR chains and are restricted by monomorphic major histocompatibility complex (MHC) …

The liver is an important immunological site that can promote immune tolerance or
activation. Natural killer (NK) cells are a major immune subset within the liver, and therefore …

Mucosal-associated invariant T (MAIT) cells have been described in liver and non-liver
diseases, and they have been ascribed antimicrobial, immune regulatory, protective, and …

Background/aims Primary sclerosing cholangitis (PSC) is a chronic inflammatory biliary
disease for which the immunopathological basis remains an enigma. Natural killer (NK) cells …

The pathogenesis of primary sclerosing cholangitis (PSC), an autoimmune liver disease,
remains unknown. The aim of this study was to characterize peripheral blood and …