Introduction The growing interest in subcutaneous delivery of larger single-dose volumes
using handheld autoinjectors raises questions about the feasible upper limits for injection …

Objective While interest in the use of wearable large-volume injectors for subcutaneous drug
delivery is increasing, it remains unclear whether and under what conditions these emerging …

The analysis of tissue mechanics in biomedical applications demands nonlinear constitutive
models able to capture the energy dissipation mechanisms, such as damage, that occur …

Subcutaneous injection of therapeutic monoclonal antibodies (mAbs) has become one of
the fastest-growing fields in the pharmaceutical industry. The transport and mechanical …

Subcutaneous injection of monoclonal antibodies (mAbs) has experienced unprecedented
growth in the pharmaceutical industry due to its benefits in patient compliance and cost …

The subcutaneous injection is the main route of administration for monoclonal antibodies
(mAbs) and several other biotherapeutics due to the patient comfort and cost-effectiveness …

The subcutaneous injection has emerged to become a feasible self-administration practice
for biotherapeutics due to the patient comfort and cost-effectiveness. However, the available …

The pharmaceutical industry has experienced a remarkable increase in the use of
subcutaneous injection of monoclonal antibodies (mAbs), attributed mainly to its advantages …

In hospitals, often drug products in intravenous (IV) bags are transported via pneumatic tube
systems (PTS). The goal of this study was to evaluate the effects of such transportation of …

Autoinjector devices are rapidly becoming the preferred method of drug delivery for a wide
array of pharmaceuticals such as monoclonal antibodies. Yet, our understanding of injection …