Nanoparticles in clinical translation for cancer therapy

D Mundekkad, WC Cho - International journal of molecular sciences, 2022 - mdpi.com
The advent of cancer therapeutics brought a paradigm shift from conventional therapy to
precision medicine. The new therapeutic modalities accomplished through the properties of …

Biomedical applications of PLGA nanoparticles in nanomedicine: advances in drug delivery systems and cancer therapy

A Narmani, R Jahedi… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction During the last decades, the ever-increasing proportion of patients with cancer
has been led to serious concerns worldwide. Therefore, the development and use of novel …

[HTML][HTML] NK cell-based tumor immunotherapy

H Zhang, L Yang, T Wang, Z Li - Bioactive materials, 2024 - Elsevier
Natural killer (NK) cells display a unique inherent ability to identify and eliminate virus-
infected cells and tumor cells. They are particularly powerful for elimination of hematological …

Current trends in PLGA based long-acting injectable products: The industry perspective

OS Muddineti, A Omri - Expert Opinion on Drug Delivery, 2022 - Taylor & Francis
Introduction Poly (lactic-co-glycolic acid)(PLGA) has been used in many long-acting drug
formulations, which have been approved by the US Food and Drug Administration (FDA) …

Mesenchymal stem cells and natural killer cells interaction mechanisms and potential clinical applications

B Abbasi, K Shamsasenjan, M Ahmadi… - Stem cell research & …, 2022 - Springer
Natural killer cells (NK cells) are innate immune cells that are activated to fight tumor cells
and virus-infected cells. NK cells also play an important role in the graft versus leukemia …

The nanocomposites designs of phytomolecules from medicinal and aromatic plants: promising anticancer-antiviral applications

A Kaplan - Beni-Suef University Journal of Basic and Applied …, 2022 - Springer
Background Nowadays, researchers are moving toward a herbal approach to cancer
treatment because of the harmful effects of synthetic anti-tumor drugs. The evaluation of …

PLGA-based drug delivery system for combined therapy of cancer: Research progress

Z Ruirui, J He, X Xu, S Li, H Peng… - Materials Research …, 2021 - iopscience.iop.org
In recent years, PLGA micro/nano particle drug delivery systems has been widely used in
cancer treatment. According to the unique properties of PLGA, carriers of various structures …

Nanoparticle-based immunoengineered approaches for combating HIV

A Bowen, EE Sweeney, R Fernandes - Frontiers in Immunology, 2020 - frontiersin.org
Highly active antiretroviral therapy (HAART) serves as an effective strategy to combat HIV
infections by suppressing viral replication in patients with HIV/AIDS. However, HAART does …

Nanosystems applied to HIV infection: prevention and treatments

MA Macchione, D Aristizabal Bedoya… - International journal of …, 2020 - mdpi.com
Sexually-transmitted infections (STIs) are a global health concern worldwide as they cause
acute diseases, infertility, and significant mortality. Among the bacterial, viral, and parasitic …

Nanodepots Encapsulating a Latency Reversing Agent and Broadly Neutralizing Antibody Enhance Natural Killer Cell Cytotoxicity Against an in vitro Model of Latent …

J Ghofrani, A Bowen, J Chen… - International journal …, 2023 - Taylor & Francis
Purpose Current antiretroviral therapies (ART) for human immunodeficiency virus (HIV) are
not curative, as the virus persists in latent reservoirs, requiring lifelong adherence to ART …