Self-inspired learning for denoising live-cell super-resolution microscopy

L Qu, S Zhao, Y Huang, X Ye, K Wang, Y Liu, X Liu… - Nature …, 2024 - nature.com
Every collected photon is precious in live-cell super-resolution (SR) microscopy. Here, we
describe a data-efficient, deep learning-based denoising solution to improve diverse SR …

Delivery and kinetics of immersion optical clearing agents in tissues: Optical imaging from ex vivo to in vivo

T Yu, X Zhong, D Li, J Zhu, VV Tuchin, D Zhu - Advanced Drug Delivery …, 2024 - Elsevier
Advanced optical imaging provides a powerful tool for the structural and functional analysis
of tissues with high resolution and contrast, but the imaging performance decreases as light …

Self-supervised denoising for multimodal structured illumination microscopy enables long-term super-resolution live-cell imaging

X Chen, C Qiao, T Jiang, J Liu, Q Meng, Y Zeng… - PhotoniX, 2024 - Springer
Detection noise significantly degrades the quality of structured illumination microscopy (SIM)
images, especially under low-light conditions. Although supervised learning based …

Zero-shot learning enables instant denoising and super-resolution in optical fluorescence microscopy

C Qiao, Y Zeng, Q Meng, X Chen, H Chen… - Nature …, 2024 - nature.com
Computational super-resolution methods, including conventional analytical algorithms and
deep learning models, have substantially improved optical microscopy. Among them …

PNR: Physics-informed Neural Representation for high-resolution LFM reconstruction

J Zhao, Z Zhao, J Wu, T Yu, H Qiao - arXiv preprint arXiv:2409.18223, 2024 - arxiv.org
Light field microscopy (LFM) has been widely utilized in various fields for its capability to
efficiently capture high-resolution 3D scenes. Despite the rapid advancements in neural …

Self-inspired learning to denoise for live-cell super-resolution microscopy

L Qu, S Zhao, Y Huang, X Ye, K Wang, Y Liu, X Liu… - bioRxiv, 2024 - biorxiv.org
Every collected photon is precious in live-cell super-resolution (SR) fluorescence
microscopy for contributing to breaking the diffraction limit with the preservation of temporal …

Multi-color fluorescence live-cell imaging in Dictyostelium discoideum

H Hashimura, S Kuwana, H Nakagawa, K Abe… - bioRxiv, 2024 - biorxiv.org
The cellular slime mold Dictyostelium discoideum, a member of the Amoebozoa, has been
extensively studied in cell and developmental biology. D. discoideum is unique in that they …

Physics-Informed Ellipsoidal Coordinate Encoding Implicit Neural Representation for high-resolution volumetric wide-field microscopy

Y Zhou, C Xu, Z Jin, Y Chen, B Zheng, M Wang… - bioRxiv, 2024 - biorxiv.org
Wide-field fluorescence microscopy through axial scanning provides a simple way for
volumetric imaging of cellular and intracellular activities, but the optical transfer function …

Ultra-low photodamage three-photon microscopy assisted by neural network for monitoring regenerative myogenesis

Y Li, keying Li, M He, C Liang, X Xie, J Qian - bioRxiv, 2024 - biorxiv.org
Three-photon microscopy (3PM) enables high-resolution three-dimensional (3D) imaging in
deeply situated and highly scattering biological specimens, facilitating precise …