Bacterial nosocomial infections: multidrug resistance as a trigger for the development of novel antimicrobials

SA Sousa, JR Feliciano, T Pita, CF Soeiro, BL Mendes… - Antibiotics, 2021 - mdpi.com
Nosocomial bacterial infections are associated with high morbidity and mortality, posing a
huge burden to healthcare systems worldwide. The ongoing COVID-19 pandemic, with the …

Monolithic conjugated microporous polymers with antibacterial activity for air filtration

H Sun, C Guo, Y Jing, A Yi, J Wang, R Jiao, J Li… - Separation and …, 2025 - Elsevier
The air pollution caused by particulate matters (PMs) poses a severe threat to the human
health. In particular, the fine particles with diameter smaller than 2.5 μm (PM 2.5) can be …

[HTML][HTML] Antimicrobial Activity of Water-Soluble Silver Complexes Bearing C-Scorpionate Ligands

AG Mahmoud, SA Sousa, MFC Guedes da Silva… - Antibiotics, 2024 - mdpi.com
The novel hydrosoluble silver coordination polymer [Ag (NO3)(μ-1κ N; 2 κN′, N ″-
TPMOH)] n (1)(TPMOH= tris (1 H-pyrazol-1-yl) ethanol) was obtained and characterized …

The new pincer-type NHCs obtained by synthesizing Ag (I)-NHC complexes with various tails containing hydroxyl or acetate derivatives: Structural properties and in …

M Donmez, M Turkyilmaz - Journal of Molecular Liquids, 2024 - Elsevier
This article discusses the synthesis, chemistry, and uses of transition metal complexes
containing functionalized N-Heterocyclic carbenes (NHCs). NHCs were obtained by …

[HTML][HTML] Antibiofilm and Antimicrobial Potentials of Novel Synthesized Sulfur Camphor Derivatives

A Duda-Madej, S Viscardi, K Pacyga… - International Journal of …, 2024 - mdpi.com
The question being posed by scientists around the world is how different chemical
modifications of naturally occurring compounds will affect their antimicrobial properties. In …

[HTML][HTML] Insights into the Dual Anticancer and Antibacterial Activities of Composites Based on Silver Camphorimine Complexes

JP Costa, SA Sousa, JH Leitão, F Marques… - Journal of Functional …, 2024 - mdpi.com
Hydroxyapatite (HAp) is a widely used biocompatible material in orthopedic composite
preparations. However, HAp composites that exhibit both anticancer and antibacterial …

Tuning the Biological Activity of Camphorimine Complexes through Metal Selection

JP Costa, T Pinheiro, MS Martins, MFNN Carvalho… - Antibiotics, 2022 - mdpi.com
The cytotoxic activity of four sets of camphorimine complexes based on the Cu (I), Cu (II), Ag
(I), and Au (I) metal sites were assessed against the cisplatin-sensitive A2780 and OVCAR3 …

Advances in Human Pathogen Control—A 21st Century Challenge

JH Leitão, JR Feliciano, N Amdare - Vaccines, 2023 - mdpi.com
The emergence of new pathogens, coupled with the reemergence of old pathogens and the
steep worldwide increase in multiple resistances to available antimicrobials, poses major …

Camphor Sulfonimine Compounds: Bottom-Up Design of MOFs from Organic Frameworks Based on X-rays and DFT-D3

JP da Costa, MFNN de Carvalho, AM Galvão - Crystals, 2023 - mdpi.com
DFT-D3 calculations based on structural X-ray diffraction data obtained for 3-oxo-
camphorsulfonyl imine (1), camphorsulfonyl chloride (2) and seven camphor sulfonimines …

Synthesis and Characterization of Camphorimine Au(I) Complexes with a Remarkably High Antibacterial Activity towards B. contaminans and P. aeruginosa

JP Costa, SA Sousa, C Soeiro, JH Leitão, AM Galvão… - Antibiotics, 2021 - mdpi.com
Fourteen new camphorimine Au (I) complexes were synthesized and characterized by
spectroscopic (NMR, FTIR) and elemental analysis. The structural arrangement of three …