The idiopathic inflammatory myopathies, including adult and juvenile dermatomyositis (DM),
polymyositis (PM), and inclusion body myositis (IBM), are rare systemic autoimmune …

The adult and juvenile myositis syndromes, commonly referred to collectively as idiopathic
inflammatory myopathies (IIMs), are systemic autoimmune diseases with the hallmarks of …

Background Treatment for autoimmune diseases such as systemic lupus erythematosus
(SLE), idiopathic inflammatory myositis, and systemic sclerosis often involves long-term …

Idiopathic inflammatory myopathies (IIM) are a heterogenous family of diseases that can
affect the muscles, skin, lungs, and joints. There have been prior attempts to classify IIMs …

Objective To assess the safety and efficacy of rituximab in a randomized, double‐blind,
placebo‐phase trial in adult and pediatric myositis patients. Methods Adults with refractory …

Objective To identify the clinical and laboratory predictors of clinical improvement in a cohort
of myositis patients treated with rituximab. Methods We analyzed data for 195 patients with …

Muscle cell death in polymyositis is induced by CD8+ cytotoxic T lymphocytes. We
hypothesized that the injured muscle fibers release pro-inflammatory molecules, which …

Abstract Objective Autoantibodies recognizing 3‐hydroxy‐3‐methylglutaryl‐coenzyme A
reductase (HMGCR) are found in patients with statin‐associated immune‐mediated …

Manual muscle testing (MMT) and hand-held dynamometry (HHD) are commonly used in
people with inflammatory myopathy (IM), but their clinimetric properties have not yet been …

Although idiopathic inflammatory myopathies (IIM) are a heterogeneous group of diseases
nearly all patients display muscle inflammation. Originally, muscle biopsy was considered as …