[HTML][HTML] What is a cell type and how to define it?

H Zeng - Cell, 2022 - cell.com
Cell types are the basic functional units of an organism. Cell types exhibit diverse
phenotypic properties at multiple levels, making them challenging to define, categorize, and …

Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology

VJ Sydnor, B Larsen, DS Bassett, A Alexander-Bloch… - Neuron, 2021 - cell.com
The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …

[HTML][HTML] A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation

Z Yao, CTJ Van Velthoven, TN Nguyen, J Goldy… - Cell, 2021 - cell.com
The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in
perception, cognition, emotion, and learning. We profiled∼ 1.3 million cells covering the …

Development of prefrontal cortex

SM Kolk, P Rakic - Neuropsychopharmacology, 2022 - nature.com
During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …

[HTML][HTML] Shared and distinct transcriptomic cell types across neocortical areas

B Tasic, Z Yao, LT Graybuck, KA Smith, TN Nguyen… - Nature, 2018 - nature.com
The neocortex contains a multitude of cell types that are segregated into layers and
functionally distinct areas. To investigate the diversity of cell types across the mouse …

An atlas of cortical arealization identifies dynamic molecular signatures

A Bhaduri, C Sandoval-Espinosa, M Otero-Garcia, I Oh… - Nature, 2021 - nature.com
The human brain is subdivided into distinct anatomical structures, including the neocortex,
which in turn encompasses dozens of distinct specialized cortical areas. Early …

Intrinsic activity development unfolds along a sensorimotor–association cortical axis in youth

VJ Sydnor, B Larsen, J Seidlitz, A Adebimpe… - Nature …, 2023 - nature.com
Animal studies of neurodevelopment have shown that recordings of intrinsic cortical activity
evolve from synchronized and high amplitude to sparse and low amplitude as plasticity …

Brain organoids: advances, applications and challenges

X Qian, H Song, G Ming - Development, 2019 - journals.biologists.com
Brain organoids are self-assembled three-dimensional aggregates generated from
pluripotent stem cells with cell types and cytoarchitectures that resemble the embryonic …

New insights into the development of the human cerebral cortex

Z Molnár, GJ Clowry, N Šestan, A Alzu'bi… - Journal of …, 2019 - Wiley Online Library
The cerebral cortex constitutes more than half the volume of the human brain and is
presumed to be responsible for the neuronal computations underlying complex phenomena …

Microstructural and functional gradients are increasingly dissociated in transmodal cortices

C Paquola, R Vos De Wael, K Wagstyl… - PLoS …, 2019 - journals.plos.org
While the role of cortical microstructure in organising neural function is well established, it
remains unclear how structural constraints can give rise to more flexible elements of …