Objective: The aim of this review was to determine whether selective serotonin reuptake
inhibitors (SSRIs) affect the ability to conceive in men and women of reproductive age, as …

Contamination of aquatic habitats with pharmaceuticals is a major environmental concern.
Recent studies have detected pharmaceutical pollutants in a wide array of ecosystems and …

Adverse effects of drugs on male reproductive system can be categorized as pre-testicular,
testicular, and post-testicular. Pre-testicular adverse effects disrupt the hypothalamic …

STUDY QUESTION Do selective serotonin reuptake inhibitor (SSRI) antidepressants affect
the function of human sperm? SUMMARY ANSWER The SSRI antidepressant Sertraline (eg …

Background Paroxetine, a selective serotonin reuptake inhibitor (SSRI) antidepressant, has
caused male sexual dysfunction; however, the paroxetine mechanisms of action in testes …

The effects of fluoxetine, one of the most prescribed selective serotonin-reuptake inhibitors
(SSRIs) during pregnancy, and its active metabolite norfluoxetine were studied on placental …

The selective serotonin reuptake inhibitor fluoxetine has been used for the treatment of
depression. Although sexual disorders have been reported in male patients, few studies …

Methods The in vitro (anti) estrogenic activity was assessed using a firefly luciferase reporter
construct in the T47D-KBluc breast cancer cell line. These cells express nuclear estrogen …

Fluoxetine (FLX) is extensively used for the treatment of a diversity of psychiatric disorders,
mainly depression. However, it can adversely affect male fertility. This study was done to …

Cryptorchidism (CO) or undescended testes is defined as the failure of one or both testes to
be positioned inside the scrotum. Typically, cryptorchidism is detected at birth or shortly …