Adipose tissue is an immunologically active organ that controls host physiology, partly
through the release of mediators termed adipokines. In obesity, adipocytes and infiltrating …

Apelin, a bioactive peptide that serves as an endogenous ligand for the apelin receptor
(APJ), is overexpressed in various types of cancers and contributes to cancer cell …

Head and neck squamous cell carcinoma (HNSCC) rank among the most prevalent types of
head and neck cancer globally. Unfortunately, a significant number of patients receive their …

Aims: Investigate the role of the apelin/APLNR axis in metabolic dysfunction-associated
steatotic liver disease (MASLD), focusing on the progression from metabolic dysfunction …

Background. Peptidergic GPCR systems are broadly distributed in the human body and
regulate numerous physiological processes by activating complex networks of intracellular …

Atherosclerosis (AS) is a progressive arterial disease characterized by chronic inflammation
and plaque formation in blood vessel walls. ELABELA, an endogenous ligand for the G …

Backgroud: Kidney transplantation is the optimal treatment for end-stage renal disease, yet
acute rejection remains a significant challenge to the survival rates of grafts. Ischemia …

Peptidergic GPCR systems are broadly distributed in the human body and regulate
numerous physiological processes by activating complex networks of intracellular …

Overweight is an urgent concern of majority of health organizations where it is rising
incidence of metabolic syndromes and diseases. Molecular genetics studies on obesity …

Untitled Page 1 Page 2 Université de Sherbrooke Le rôle du système apelinergique sur la
revascularisation à la suite d’une ischémie d’un membre inférieur et sur la guérison de plaie …