Aflatoxins: A global concern for food safety, human health and their management

P Kumar, DK Mahato, M Kamle, TK Mohanta… - Frontiers in …, 2017 - frontiersin.org
The aflatoxin producing fungi, Aspergillus spp., are widely spread in nature and have
severely contaminated food supplies of humans and animals, resulting in health hazards …

Clustered pathway genes in aflatoxin biosynthesis

J Yu, PK Chang, KC Ehrlich, JW Cary… - Applied and …, 2004 - Am Soc Microbiol
Affatoxins, a group of polyketide-derived furanocoumarins (Fig. 1), are the most toxic and
carcinogenic compounds among the known mycotoxins. Among the at least 16 structurally …

Current understanding on aflatoxin biosynthesis and future perspective in reducing aflatoxin contamination

J Yu - Toxins, 2012 - mdpi.com
Traditional molecular techniques have been used in research in discovering the genes and
enzymes that are involved in aflatoxin formation and genetic regulation. We cloned most, if …

Genetics and physiology of aflatoxin biosynthesis

GA Payne, MP Brown - Annual review of phytopathology, 1998 - annualreviews.org
▪ Abstract Aflatoxins are the most thoroughly studied mycotoxins. Elegant early research on
the biosynthetic scheme of the pathway has allowed a molecular characterization of …

Aflatoxin biosynthesis: current frontiers

LV Roze, SY Hong, JE Linz - Annual review of food science and …, 2013 - annualreviews.org
Aflatoxins are among the principal mycotoxins that contaminate economically important food
and feed crops. Aflatoxin B1 is the most potent naturally occurring carcinogen known and is …

Molecular characterization of aflR, a regulatory locus for aflatoxin biosynthesis

CP Woloshuk, KR Foutz, JF Brewer… - Applied and …, 1994 - Am Soc Microbiol
Aflatoxins belong to a family of decaketides that are produced as secondary metabolites by
Aspergillus flavus and A. parasiticus. The aflatoxin biosynthetic pathway involves several …

Enzymology and molecular biology of aflatoxin biosynthesis

RE Minto, CA Townsend - Chemical reviews, 1997 - ACS Publications
Enzymology and Molecular Biology of Aflatoxin Biosynthesis | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications …

Molecular genetic analysis and regulation of aflatoxin biosynthesis

D Bhatnagar, KC Ehrlich, TE Cleveland - Applied microbiology and …, 2003 - Springer
Aflatoxins, produced by some Aspergillus species, are toxic and extremely carcinogenic
furanocoumarins. Recent investigations of the molecular mechanism of AFB biosynthesis …

Comparative mapping of aflatoxin pathway gene clusters in Aspergillus parasiticus and Aspergillus flavus

J Yu, PK Chang, JW Cary, M Wright… - Applied and …, 1995 - Am Soc Microbiol
Aflatoxins are toxic and carcinogenic secondary metabolites produced by the fungi
Aspergillus flavus and A. parasiticus. Aflatoxins are synthesized by condensation of acetate …

Detection of aflatoxigenic molds in grains by PCR

R Shapira, N Paster, O Eyal… - Applied and …, 1996 - Am Soc Microbiol
Aflatoxins are carcinogenic metabolites produced by several members of the Aspergillus
flavus group in grains and floods. Three genes, ver-1, omt-1, and apa-2, coding for key …