Alternative pre-mRNA splicing in stem cell function and therapeutic potential: A critical review of current evidence

L Cui, Y Zheng, R Xu, Y Lin, J Zheng, P Lin… - International Journal of …, 2024 - Elsevier
Alternative splicing is a crucial regulator in stem cell biology, intricately influencing the
functions of various biological macromolecules, particularly pre-mRNAs and the resultant …

Tissue-and cell-specific whole-transcriptome meta-analysis from brain and retina reveals differential expression of dystrophin complexes and new dystrophin spliced …

C García-Cruz, J Aragón, S Lourdel… - Human Molecular …, 2023 - academic.oup.com
The large DMD gene encodes a group of dystrophin proteins in brain and retina, produced
from multiple promoters and alternative splicing events. Dystrophins are core components of …

Expression of Dystrophin Dp71 Splice Variants Is Temporally Regulated During Rodent Brain Development

M González-Reyes, J Aragón, A Sánchez-Trujillo… - Molecular …, 2024 - Springer
Dystrophin Dp71 is the major product of the Duchenne muscular dystrophy (DMD) gene in
the brain, and its loss in DMD patients and mouse models leads to cognitive impairments …

Characterization of Dystrophin Dp71 Expression and Interaction Partners in Embryonic Brain Development: Implications for Duchenne/Becker Muscular Dystrophy

T Fujimoto, M Mori, M Tonosaki, T Yaoi, K Nakano… - Molecular …, 2025 - Springer
Duchenne/Becker muscular dystrophy (DMD/BMD) manifests progressive muscular
dystrophy and non-progressive central nervous disorder. The neural disorder is possibly …

Generation of dystrophin short product-specific tag-insertion mouse: distinct Dp71 glycoprotein complexes at inhibitory postsynapse and glia limitans

T Fujimoto, T Yaoi, K Nakano, T Arai… - Cellular and Molecular …, 2022 - Springer
Duchenne muscular dystrophy (DMD), the most severe form of dystrophinopathies, is a fatal
X-linked recessive neuromuscular disorder characterized by progressive muscle …

Nuclear Small Dystrophin Isoforms during Muscle Differentiation

T Donandt, V Todorow, S Hintze, A Graupner… - Life, 2023 - mdpi.com
Mutations in the DMD gene can cause Duchenne or Becker muscular dystrophy (DMD/BMD)
by affecting the giant isoform of dystrophin, a protein encoded by the DMD gene. The role of …

[PDF][PDF] César García-Cruz1, 2, Jorge Aragón1, Sophie Lourdel2, Ahrmad Annan2, Jérôme E. Roger2, 3,*, Cecilia Montanez1,* and

C Vaillend - Human Molecular Genetics, 2023 - pdfs.semanticscholar.org
The large DMD gene encodes a group of dystrophin proteins in brain and retina, produced
from multiple promoters and alternative splicing events. Dystrophins are core components of …

[PDF][PDF] meta-analysis from brain and retina reveals differential expression of dystrophin complexes and new dystrophin spliced isoforms

C García-Cruz, J Aragón, S Lourdel, A Annan… - 2022 - researchgate.net
The large DMD gene encodes a group of dystrophin proteins in brain and retina, produced
from multiple promoters and alternative splicing events. Dystrophins are core components of …

[引用][C] Identificación de las isoformas de la distrofina Dp40 que se expresan durante la diferenciación de las células PC12

IS Romero Flores - 2021 - … (MC)--Centro de Investigación y de …