[HTML][HTML] Intein based fusion proteins: great tags for the soluble production and convenient purification of recombinant proteins
F Shafiee, S Sharifi, A Amini - Iranian Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Background: The main problem in the recombinant protein expression in E. coli strains,
especially for high-yield production, is the accumulation in un-folded and inactive inclusion …
especially for high-yield production, is the accumulation in un-folded and inactive inclusion …
A wearable gamma radiation-responsive granulocyte colony-stimulating factor microneedle system protecting against ionizing radiation-induced injury
X Yu, L Zhu, X Liang, B Yuan, M Li, S Hu, P Ding, L Du… - Acta Biomaterialia, 2022 - Elsevier
Exposure to a nuclear accident or a radiological attack may cause serious death events due
to ionizing radiation-induced injury and acute radiation syndrome (ARS). Recombinant …
to ionizing radiation-induced injury and acute radiation syndrome (ARS). Recombinant …
Recombinant production of interleukin-1 receptor antagonist in fusion to albumin binding domain with potential affinity to human serum albumin
F Shafiee, A Yazdani - Research in Pharmaceutical Sciences, 2024 - journals.lww.com
Background and purpose: Anakinra must be injected daily due to its short half-life and this
leads to lower patient compliance. Therefore, the aim of this study was to produce an …
leads to lower patient compliance. Therefore, the aim of this study was to produce an …
Recombinant Production and One Step Purification of IL-1Ra in Escherichia coli and Evaluation its IL-1 Antagonizing Efficacy
R Adelnia, F Shafiee - Iranian Journal of Immunology, 2021 - iji.sums.ac.ir
Background: Anakinra (Kineret®), an IL-1 receptor antagonist, is the first FDA approved
biologic drug for antagonizing IL-1 effects in patients with Rheumatoid arthritis. Notably, the …
biologic drug for antagonizing IL-1 effects in patients with Rheumatoid arthritis. Notably, the …
Combinatorial ethanol treatment increases the overall productivity of recombinant hG-CSF in E. coli: a comparative study
Human granulocyte colony-stimulating factor (hG-CSF) is a cytokine that regulates the
proliferation, maturation, and differentiation of precursor cells to neutrophils. In the present …
proliferation, maturation, and differentiation of precursor cells to neutrophils. In the present …
Recombinant Production of IL-1Ra in Fusion to Albumin Binding Domain for Its Extended Half-Life
F Shafiee, A Yazdani - 2021 - researchsquare.com
Background: Anakinra, a FDA approved biological drug for Rheumatoid Arthritis, must be
injected daily due to its short Half-life, leads to the lower patient compliance. So, the aim of …
injected daily due to its short Half-life, leads to the lower patient compliance. So, the aim of …