Healing and regeneration of bone injuries, particularly those that are associated with large
bone defects, are a complicated process. There is growing interest in the application of …

Atrial natriuretic peptide (ANP) a cardiovascular hormone mainly secreted by heart atria in
response to stretching forces induces potent diuretic, natriuretic and vasorelaxant effects …

Due to globalization and sophisticated western and sedentary lifestyle, metabolic syndrome
has emerged as a serious public health challenge. Obesity is significantly increasing …

Cisplatin (CDDP)-based chemotherapy is the preferred treatment strategy for advanced
stage gastric cancer (GC) patients. Despite the efficacy of chemotherapy, the development of …

Extracellular vesicles (EVs) such as microvesicles (MIVs) play an important role in
intercellular communications. MIVs are small membrane vesicles sized 100–1000 nm in …

Atrial natriuretic peptide (ANP) is a cardiac hormone controlling blood volume and pressure
in mammals. It is still unclear whether ANP controls cold-induced thermogenesis in vivo …

Intraocular drug delivery is a promising approach for treatment of ocular diseases.
Chemotherapeutic drugs used in retinoblastoma (RB) treatment often lead to side effects …

Respiratory syncytial virus (RSV) has been reported to infect human mesenchymal stem
cells (MSCs) but the consequences are poorly understood. MSCs are present in nearly …

In this work, a 3D MCTS-CCA system was constructed by culturing multi-cellular tumor
spheroid (MCTS) in the chitosan/collagen/alginate (CCA) fibrous scaffold for anticancer drug …

Angiogenesis is involved in the development, progression and metastasis of various human
cancers. Herein, we report the discovery of glipizide, a widely used drug for type 2 diabetes …