Understanding the brain circuitry that underlies reward is critical to improve treatment for many common health issues, including obesity, depression, and addiction. Here we focus …
Y Zhu, CFR Wienecke, G Nachtrab, X Chen - Nature, 2016 - nature.com
Chronic opiate use induces opiate dependence, which is characterized by extremely unpleasant physical and emotional feelings after drug use is terminated. Both the rewarding …
This article reviews the anatomical connections of the paraventricular nucleus of the thalamus (PVT) and discusses some of the connections by which the PVT could influence …
The thalamus was subdivided into three major groups: sensorimotor nuclei (or principal/relay nuclei), limbic nuclei and nuclei bridging these two domains. Limbic nuclei of …
One decade ago, our laboratory provided the first direct evidence linking orexin/hypocretin signaling with drug seeking by showing that activation of these neurons promotes …
AK Zinsmaier, Y Dong, YH Huang - Molecular psychiatry, 2022 - nature.com
Cocaine craving, seeking, and relapse are mediated, in part, by cocaine-induced adaptive changes in the brain reward circuits. The nucleus accumbens (NAc) integrates and …
Written for practitioners in the field, this critically acclaimed bestseller provides authoritative information focused on the investigation of drug-related deaths and practical approaches to …
S Li, GJ Kirouac - Brain Structure and Function, 2012 - Springer
The paraventricular nucleus of the thalamus (PVT) is part of a group of midline and intralaminar thalamic nuclei implicated in arousal and attention. Recent research points to …
X Dong, S Li, GJ Kirouac - Brain Structure and Function, 2017 - Springer
The paraventricular nucleus of the thalamus (PVT) is a midline thalamic nucleus with dense projections to the nucleus accumbens (NAc), dorsolateral region of the bed nucleus of the …