[HTML][HTML] The Dual effects of exosomes on Glioma: a Comprehensive Review

M Luo, X Luan, G Jiang, L Yang, K Yan, S Li… - Journal of …, 2023 - ncbi.nlm.nih.gov
Glioma is a frequently occurring type of cancer that affects the central nervous system.
Despite the availability of standardized treatment options including surgical resection …

Microglial extracellular vesicles as modulators of brain microenvironment in glioma

M Catalano, C Serpe, C Limatola - International Journal of Molecular …, 2022 - mdpi.com
Microglial cells represent the resident immune elements of the central nervous system,
where they exert constant monitoring and contribute to preserving neuronal activity and …

A prognostic neural epigenetic signature in high-grade glioma

R Drexler, R Khatri, T Sauvigny, M Mohme, CL Maire… - Nature Medicine, 2024 - nature.com
Neural–tumor interactions drive glioma growth as evidenced in preclinical models, but
clinical validation is limited. We present an epigenetically defined neural signature of …

Exosomal TNF-α mediates voltage-gated Na+ channel 1.6 overexpression and contributes to brain tumor–induced neuronal hyperexcitability

CAS Trivino, R Spelat, F Spada, C D'Angelo… - The Journal of Clinical …, 2024 - jci.org
Patients affected by glioma frequently experience epileptic discharges; however, the causes
of brain tumor–related epilepsy (BTRE) are still not completely understood. We investigated …

Epilepsy in gliomas: recent insights into risk factors and molecular pathways

R Rudà, F Bruno, A Pellerino - Current Opinion in Neurology, 2023 - journals.lww.com
Epilepsy in gliomas: recent insights into risk factors and m... : Current Opinion in Neurology
Epilepsy in gliomas: recent insights into risk factors and molecular pathways : Current Opinion …

Emergence of collective self-oscillations in minimal lattice models with feedback

D Sinelshchikov, A Poggialini, MF Abbate… - Physical Review E, 2023 - APS
The emergence of collective oscillations and synchronization is a widespread phenomenon
in complex systems. While widely studied in the setting of dynamical systems, this …

[PDF][PDF] Extracellular vesicles as modulators of glioblastoma progression and tumor microenvironment

J Dai, Y Jiang, H Hu, S Zhang… - Pathology and Oncology …, 2024 - por-journal.com
Gliomas are common central nervous system (CNS) tumors that are classified according to
morphology and molecular characteristics, graded according to malignancy. The World …

Altered extracellular matrix as an alternative risk factor for epileptogenicity in brain tumors

JM de Jong, DWM Broekaart, A Bongaarts… - Biomedicines, 2022 - mdpi.com
Seizures are one of the most common symptoms of brain tumors. The incidence of seizures
differs among brain tumor type, grade, location and size, but paediatric-type diffuse low …

[HTML][HTML] Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability

R Drexler, R Khatri, T Sauvigny, M Mohme, CL Maire… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Neural-tumor interactions drive glioma growth as evidenced in preclinical models, but
clinical validation is nascent. We present an epigenetically defined neural signature of …

Mechanisms of Glioblastoma Replication: Ca2+ Flares and Cl Currents

Y Li, CA Sanchez Triviño, A Hernandez… - Molecular Cancer …, 2024 - aacrjournals.org
Glioblastoma (GBM) is amongst the deadliest types of cancers, with no resolutive cure
currently available. GBM cell proliferation in the patient's brain is a complex phenomenon …