Skeletal muscle performance and ageing

M Tieland, I Trouwborst, BC Clark - Journal of cachexia …, 2018 - Wiley Online Library
The world population is ageing rapidly. As society ages, the incidence of physical limitations
is dramatically increasing, which reduces the quality of life and increases healthcare …

The effects of inflammation, aging and oxidative stress on the pathogenesis of diabetes mellitus (type 2 diabetes)

M Halim, A Halim - Diabetes & metabolic syndrome: clinical research & …, 2019 - Elsevier
Diabetes mellitus is seen to be prevalent among the different epidemics. The prevalence
rate of the diabetes mellitus is seen to be increasing in different regions of the world. Type 2 …

[HTML][HTML] A novel evolutionary ensemble prediction model using harmony search and stacking for diabetes diagnosis

Z Zhang, Y Lu, M Ye, W Huang, L Jin, G Zhang… - Journal of King Saud …, 2024 - Elsevier
Diabetes is a dreaded disease that can be identified by elevated blood glucose levels in the
blood, and undiagnosed diabetes can cause a host of related complications, such as …

Liraglutide provides cardioprotection through the recovery of mitochondrial dysfunction and oxidative stress in aging hearts

A Durak, B Turan - Journal of physiology and biochemistry, 2023 - Springer
Abstract Glucagon-like peptide-1 receptor (GLP-1R) agonists improve cardiovascular
dysfunction via the pleiotropic effects behind their receptor action. However, it is unknown …

Reversine ameliorates hallmarks of cellular senescence in human skeletal myoblasts via reactivation of autophagy

N Rajabian, D Choudhury, I Ikhapoh, S Saha… - Aging …, 2023 - Wiley Online Library
Cellular senescence leads to the depletion of myogenic progenitors and decreased
regenerative capacity. We show that the small molecule 2, 6‐disubstituted purine, reversine …

Insulin resistance is associated with gut permeability without the direct influence of obesity in young adults

L Mkumbuzi, MMO Mfengu, GA Engwa… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Objective Recent findings have associated insulin resistance and obesity with increased gut
permeability. However, it still remains unclear whether obesity may be the underlining factor …

A Caputo (discretization) fractional-order model of glucose-insulin interaction: numerical solution and comparisons with experimental data

MH Alshehri, FZ Duraihem, A Alalyani… - Journal of Taibah …, 2021 - Taylor & Francis
In this paper, we investigate a (discretization) Caputo fractional glucose-insulin model
qualitatively with incommensurate orders that appear in Bergman's minimal model. After …

Intracellular redistribution of left ventricular connexin 43 contributes to the remodeling of electrical properties of the heart in insulin-resistant elderly rats

D Billur, Y Olgar, B Turan - Journal of Histochemistry & …, 2022 - journals.sagepub.com
The correlation between long-QT and connexin 43 (Cx43) status and localization in elderly
rats was determined to demonstrate a correlation between insulin resistance (IR), ischemia …

Increased OCT3 Expression in Adipose Tissue With Aging: Implications for Catecholamine and Lipid Turnover and Insulin Resistance in Women

F Ahmed, M Vranic, S Hetty, A Mathioudaki… - …, 2024 - academic.oup.com
Background Catecholamine-stimulated lipolysis is reduced with aging, which may promote
adiposity and insulin resistance. Organic cation transporter 3 (OCT3), which is inhibited by …

[HTML][HTML] Metabolic switching is impaired by aging and facilitated by ketosis independent of glycogen

A Hernandez, L Truckenbrod, Q Federico… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
The ability to switch between glycolysis and ketosis promotes survival by enabling
metabolism through fat oxidation during periods of fasting. Carbohydrate restriction or stress …