Mycobacterium tuberculosis uses sophisticated secretion systems, named 6 kDa early
secretory antigenic target (ESAT6) protein family secretion (ESX) systems (also known as …

Mycobacterium tuberculosis (Mtb), the etiological agent of human tuberculosis (TB), has
plagued humans for thousands of years. TB still remains a major public health problem in …

Tuberculosis remains one of the leading causes of mortality worldwide, and, despite its
clinical significance, there are still significant gaps in our understanding of pathogenic and …

Given the encouraging clinical results of both candidate subunit vaccines and revaccination
with Bacillus Calmette-Guérin (BCG) against tuberculosis (TB), there is support for …

Tuberculosis (TB), caused by the intracellular bacterium Mycobacterium tuberculosis (Mtb),
remains a major health threat. A live, attenuated mycobacterium known as Bacille Calmette …

Mycobacterium tuberculosis, the bacterium responsible for tuberculosis, is one of the most
successful pathogens in human history. An extremely resilient cell wall and highly evolved …

Mycobacterium tuberculosis is a major, globally spread, aerosol-transmitted human
pathogen, thought to have evolved by clonal expansion from a Mycobacterium canettii-like …

The causative agent of human tuberculosis, Mycobacterium tuberculosis, has a complex
lipid-rich diderm envelope, which acts as a major barrier protecting the bacterium against …

Tuberculosis (TB) is a global health emergency. Up to one-third of the world's population is
infected with Mycobacterium tuberculosis, and the pathogen continues to kill 1.5 million …

Live attenuated and killed whole-cell vaccines (WCVs) offer promising vaccination strategies
against tuberculosis. A number of WCV candidates, based on recombinant bacillus Calmette …