Alcohol consumption is a predominant etiological factor in the pathogenesis of chronic liver
diseases, resulting in fatty liver, alcoholic hepatitis, fibrosis/cirrhosis, and hepatocellular …

The history of drug metabolism began in the 19th Century and developed slowly. In the mid-
20th Century the relationship between drug metabolism and toxicity became appreciated …

The risk assessment of chemical carcinogens is one major task in toxicology. Even though
exposure has been mitigated effectively during the last decades, low levels of carcinogenic …

Chronic alcohol abuse causes liver disease that progresses from simple steatosis through
stages of steatohepatitis, fibrosis, cirrhosis, and eventually hepatic failure. In addition …

DNA damage plays a major role in various pathophysiological conditions including
carcinogenesis, aging, inflammation, diabetes and neurodegenerative diseases. Oxidative …

The water-soluble Morchella esculenta polysaccharide 2 (MEP2) was purified and isolated
from an aqueous extract of the Morchella esculenta fruiting bodies. MEP2, having a …

Alcoholic liver disease (ALD) is a multifaceted disease that is characterized by hepatic
steatosis or fat deposition and hepatitis or inflammation. Over the past decade, multiple lines …

The designation of acetaldehyde associated with the consumption of alcoholic beverages as
“carcinogenic to humans”(Group 1) by the International Agency for Research on Cancer …

Oxidative stress is one of the important factors in the development of alcoholic liver disease.
The production of reactive oxygen species and other free radicals is an important feature of …

Epidemiological studies have identified chronic alcohol consumption as a significant risk
factor for cancers of the upper aerodigestive tract, including the oral cavity, pharynx, larynx …