Most pharmaceuticals are given using short-acting formulations that require frequent
administration, which can negatively affect patient compliance and increase failure risks …

The purpose of this review is to introduce the functionalities of hyaluronic acid (HA) and its
potential application as an effective carrier for topical/transdermal delivery. Specifically …

The intrinsic properties of therapeutic proteins generally present a major impediment for
transdermal delivery, including their relatively large molecule size and susceptibility to …

While the peptide and protein therapeutic market has developed significantly in the past
decades, delivery has limited their use. Although oral delivery is preferred, most are …

Microneedles (MNs) as a minimally invasive tool have drawn increasing attention recently.
They possess many prominent advantages, including pain-free, self-administration, and …

In recent years, there has been a surge in the research and development of microneedles
(MNs), a transdermal delivery system that combines the technology of transdermal patches …

The global market of pharmaceutical biologics has expanded significantly during the last few
decades. Currently, pharmaceutical biologic products constitute an indispensable part of the …

Traditionally, the skin is considered as a protective barrier which acts as a highly
impermeable region of the human body. But in recent times, it is recognized as a specialized …

Hyaluronic acid (HA) hydrogels are interesting delivery systems for topical applications.
Besides moisturizing the skin and improving wound healing, HA facilitates topical drug …

Transdermal drug delivery is a viable and clinically proven route of administration. This route
specifically requires overcoming the mechanical barrier provided by the Stratum Corneum of …