In the late 19th century, a number of investigators were working on perfecting isolated heart
model, but it was Oscar Langendorff who, in 1895, pioneered the isolated perfused …

The isolated perfused mammalian heart preparation was established in 1897 by Oscar
Langendorff. The method was developed on the basis of the isolated perfused frog heart …

1. The yield of mitochondria isolated from perfused hearts subjected to 30 min ischaemia
followed by 15 min reperfusion was significantly less than that for control hearts, and this …

Owing to the considerable potential for manipulating the murine genome and, as a
consequence, the increasing availability of genetically modified models of cardiovascular …

Aims Our aim was to determine the contribution of the three angiotensin (Ang) II receptor
subtypes (AT1a, AT1b, AT2) to coronary responsiveness, cardiac histopathology, and tissue …

Androgenic anabolic steroids (AAS) are often used by athletes to enhance athletic
performance but are strongly associated with detrimental cardiovascular effects including …

The contribution of Na-activated K channel, the furosemide-sensitive (Na-K-Cl) cotransport,
and Na-K pump to extracellular potassium accumulation during global ischemia was …

The role of histamine as a newly recognized sympathetic neurotransmitter has been
presented previously, and its postsynaptic effects greatly depended on the activities of …

Background Appropriate cardiac hypertrophy (CH) is necessary in several clinical settings,
such as pulmonary artery banding in the two-stage arterial switch operation for transposition …

1 The cardiovascular actions of U‐50,488 H, a κ‐receptor agonist, were studied in rat
isolated perfused hearts, and in anaesthetized rats, over concentrations or doses generally …