Cellular and molecular actions of methylene blue in the nervous system
Methylene Blue (MB), following its introduction to biology in the 19th century by Ehrlich, has
found uses in various areas of medicine and biology. At present, MB is the first line of …
found uses in various areas of medicine and biology. At present, MB is the first line of …
Pathophysiology of septic shock
JA Russell, B Rush, J Boyd - Critical care clinics, 2018 - criticalcare.theclinics.com
Pathophysiology of Septic Shock - Critical Care Clinics Skip to Main Content Skip to Main
Menu Advertisement Critical Care Clinics Log in Register Log in Subscribe Claim Main menu …
Menu Advertisement Critical Care Clinics Log in Register Log in Subscribe Claim Main menu …
Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor …
H Kimura, A Weisz, Y Kurashima… - Blood, The Journal …, 2000 - ashpublications.org
Nitric oxide (NO) regulates production of vascular endothelial growth factor (VEGF) by
normal and transformed cells. We demonstrate that NO donors may up-regulate the activity …
normal and transformed cells. We demonstrate that NO donors may up-regulate the activity …
Alternative mitochondrial electron transfer as a novel strategy for neuroprotection
Neuroprotective strategies, including free radical scavengers, ion channel modulators, and
anti-inflammatory agents, have been extensively explored in the last 2 decades for the …
anti-inflammatory agents, have been extensively explored in the last 2 decades for the …
Ophidian envenomation strategies and the role of purines
SD Aird - Toxicon, 2002 - Elsevier
Snake envenomation employs three well integrated strategies: prey immobilization via
hypotension, prey immobilization via paralysis, and prey digestion. Purines (adenosine …
hypotension, prey immobilization via paralysis, and prey digestion. Purines (adenosine …
cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase.
The L-arginine: nitric oxide (NO) pathway is believed to exert many of its physiological
effects via stimulation of the soluble guanylyl cyclase (SGC); however, the lack of a selective …
effects via stimulation of the soluble guanylyl cyclase (SGC); however, the lack of a selective …
[HTML][HTML] Nitric oxide regulates cardiac Ca2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation.
PF Mery, C Pavoine, L Belhassen, F Pecker… - Journal of Biological …, 1993 - Elsevier
The effects of the nitric oxide (NO) donor 3-morpholino-sydnonimine (SIN-1) on the L-type
Ca2+ current (ICa) were examined in frog ventricular myocytes under basal and …
Ca2+ current (ICa) were examined in frog ventricular myocytes under basal and …
Multiple Mechanisms of Na+ Channel– Linked Long-QT Syndrome
Inheritable long-QT syndrome (LQTS) is a disease in which delayed ventricular
repolarization leads to cardiac arrhythmias and the possibility of sudden death. In the …
repolarization leads to cardiac arrhythmias and the possibility of sudden death. In the …
Methylene blue improves the hepatopulmonary syndrome
P Schenk, C Madl, S Rezaie-Majd, S Lehr… - Annals of Internal …, 2000 - acpjournals.org
Background: The hypoxemia of the hepatopulmonary syndrome, seen in patients with
severe chronic liver dysfunction, results from widespread pulmonary vasodilation. No …
severe chronic liver dysfunction, results from widespread pulmonary vasodilation. No …
Selective iNOS inhibition for the treatment of sepsis-induced acute kidney injury
S Heemskerk, R Masereeuw, FGM Russel… - Nature Reviews …, 2009 - nature.com
The incidence and mortality of sepsis and the associated development of acute kidney injury
(AKI) remain high, despite intense research into potential treatments. Targeting the …
(AKI) remain high, despite intense research into potential treatments. Targeting the …