Steroid hormones regulate essential physiological processes and inadequate levels are
associated with various pathological conditions. Consequently, the process of steroid …

During fetal testis development, fetal Leydig cells (FLCs) are found to be originated from
multiple progenitor cells. FLC specification and function are under tight regulation of specific …

Cell differentiation and acquisition of specialized functions are inherent steps in events that
lead to normal tissue development and function. These processes require accurate …

The members of myocyte Enhancer Factor 2 (MEF2) protein family was previously believed
to function in the development of heart and muscle. Recent reports indicate that they are …

The insecticide acetamiprid is used to control noxious agricultural pests. However, it can
cause mammalian toxicity. We evaluated the reproductive toxicity of acetamiprid in adult …

In this review we will consider the gene mutations responsible for the non-syndromic forms
of disorders of sex development (DSD) and how recent genetic findings are providing …

Endoplasmic reticulum (ER) stress generally occurs in secretory cell types. It has been
reported that Leydig cells, which produce testosterone in response to human chorionic …

Defining how genes get turned on and off in a correct spatiotemporal manner is integral to
our understanding of the development, differentiation, and function of different cell types in …

Spermatogenesis is a complex and elaborate differentiation process and is critical for male
fertility. The hypothalamic-pituitary–gonadal axis serves as a significant neuroendocrine …

Butyric acid (BA), one of the short chain fatty acids (SCFAs), has positive actions on the
metabolism, inflammation, etc. However, whether it influences the reproductive physiology …